The Human Brain During the Third Trimester

Claustru

m

Claustru

m

PutamenPutamen

Putam

en

Putam

en

FFoorrnniixx

Forn

ix

Forn

ix

Ex

ter

na

l^ c

ap

su

le

Ex

ter

na

l^ c

ap

su

le

Exter

nal ca

psule

Exter

nal ca

psule Caudate

(tail)

Caudate

(tail)

Pr

ete

ctu

m

Pr

ete

ctu

m

Pr

etectu

m

Pr

etectu

m

Lateral ve ntricle

Superior colliculus

Optic nerve layer

Superficial gray layer

Deep gray layer

Middle gray layer

Middle white layer

Deep white layer

Zonal layer

CerCerebral aqueducebral aqueductt

Subcommissural orga n

Lateral fissure

Lateral f

issure

Interhemispheric fissure

Cortical plate

(orbital gyrus)

White matter

(orbital gyrus)

VVe ntral tenia tectaentral tenia tecta

Claustru

m

Claustru

m

IInnssuulalarr ggyyrruuss

Choroid plexus

Stria

terminalis

Stria

terminalis

BBA SAL GANGLIASAL GANGLIAA

THALAMUSTHALAMUS

Third ventricle

POSTERIOR

COMPLEX

POSTERIOR

COMPLEX

Lateral migratory stream

(infiltrates the claustrum, endopiri-

form nucleus and the external capsule)

Lateral migratory stream
(in the ve ntrolateral frontal lobe)

Diagonal band of Broca

(vertical limb)

Diagonal band of Broca

(vertical limb)

D

ia

go

n

al

b

an

d^

of

B

ro

ca

(h

or

iz

on

ta

l^ l

im

b)

D

ia

go

n

al

b

an

d^

of

B

ro

ca

(h

or

iz

on

ta

l^ l

im

b)

LaLarge island of Callejarge island of Calleja

Dorsomedial

nucleus

Dorsomedial

nucleus

A

nt

er

io

r

co

m

m

is

su

re

A

nt

er

io

r

co

m

m

is

su

re

Parahippocampal

gyrus

Parahippocampal

gyrus

Dentate gyrus

Ammon's horn

SSuubbccaalllloossaall^ aarreeaa

Nucleus

accumbens

Nucleus

accumbens

N

u

c

le

u

s

a

c

c

u

m

b

e

n

s

N

u

c

le

u

s

a

c

c

u

m

b

e

n

s

G

lob

us

p

al

lid

us

(in

te

rn

al

se

gm

en

t)

G

lob

us

p

al

lid

us

(in

te

rn

al

se

gm

en

t)

PPerieriventricular nucleuventricular nucleuss

PrPreoptic eoptic rrecessecess PREOPTIC

AREA

PREOPTIC

AREA HYPHYPOOTHALAMUSTHALAMUS

MIDBRAIMIDBRAINN

Lamina terminalis

Medial

forebrain bundle?

Medial

forebrain bundle?

TECTU

M

TECTU

M

TEGMENTUMTEGMENTUM

Lateralh

ypo

thala

mica

rea

Lateralh

ypo

thala

mica

rea

Medial

geniculate

body

Medial

geniculate

body

Lateral

geniculate

body

Lateral

geniculate

body

C

e

re

b

r

a

l

p

ed

u

n

c

le

C

e

re

b

r

a

l

p

ed

u

n

c

le

S

u

b

th

al

am

ic

n

u

cl

eu

s

S

u

b

th

al

am

ic

n

u

cl

eu

s

S

U

B

T

H

A

L

A

M

U

S

S

U

B

T

H

A

L

A

M

U

S

Basal nucleus

of Meynert

Basal nucleus

of Meynert

V

en

tr

a

l (^) s
tr
ia
tu
m
V
en
tr
a
l (^) s
tr
ia
tu
m
Glob
us pallidus
Glob
us pallidus
Central
gray
Central
gray
Endopirirorm
nucleus
Endopirirorm
nucleus
Red
nucleus
Red
nucleus
Red
nucleus
Red
nucleus
Oculomotor nuclear
complex (III)
Oculomotor nuclear
complex (III)
Mesencephalic
nucleus (V)
Mesencephalic
nucleus (V)
Medial longitudinal
fasciculus
Medial longitudinal
fasciculus
Zona
incerta
Zona
incerta
M
ed
ul
lar
ylamina
M
ed
ul
lar
ylamina
nI
te
nr
a
lc
a
sp
u
le
(p
os
te
ri
o
r
lim
b
)
nI
te
nr
a
lc
a
sp
u
le
(p
os
te
ri
o
r
lim
b
)

A

n

as

le

n

ti

c

u

la

r

is

A

n

as

le

n

ti

c

u

la

r

is

S

U

B

S

T

A

N

T

IA

I

N

N

O

M

IN

A

T

A

S

U

B

S

T

A

N

T

IA

I

N

N

O

M

IN

A

T

A

Lateral migratory stream

Primary olfactory

cortex (piriform)

Primary olfactory

cortex (piriform)

Primary olfactory

cortex (piriform)

Primary olfactory

cortex (piriform)

Ha

ben

ulo-

inte

rpe

dun

• 
  

cul

ar (^) t
ract
Ha
ben
ulo-
inte
rpe
dun

• 
  

cul

ar (^) t
ract
M
ed
ia
l l
em
ni
sc
us
M
ed
ia
l l
em
ni
sc
us
Interpeduncular
nucleus?
Interpeduncular
nucleus?
Ventral
striatum
Ve ntral
striatum
Islands of CallejaIslands of Calleja

O

lf

ac

to

r

y

tu

b

er

cl

e

O

lf

ac

to

r

y

tu

b

er

cl

e

A

nt

er

io

r

co

m

mi

ssu

re

(te

mp

ora

llim

b)

A

nt

er

io

r

co

m

mi

ssu

re

(te

mp

ora

llim

b)

White matter

Layer I

Cortical plate

Germinal and transitional structuGerminal and transitional structurres ines in italicsitalics

M

e

ye

r'

s^

lo

op

(v

is

u

a

l^ r

a

d

ia

ti

o

n

)

M

e

ye

r'

s^

lo

op

(v

is

u

a

l^ r

a

d

ia

ti

o

n

)

Te mporal neuroepithelium

and subventricular zone

Pa rahippocampal neuro-

epithelium and

subventricular zone

Te mporal stratified

transitional field

Pa rahippocampal stratified

transitional field

Stem cells of

choroid plexus

Stem cells of

choroid plexus

Fo rnical glioepithelium

PPo sterior striatal neuroepithelium and subvosterior striatal neuroepithelium and subventricular zoneentricular zone

Alve ar glioepithelium

Subgranular zone

Strionuclear

glioepithelium

Strionuclear

glioepithelium

Reticular

formation

Reticular

formatio n

Fr ontal neuroepithelium

and subventricular zone

Fr ontal stratified

transitional field

Rostral migratory stream

HIPPO-

CAMPUS

HIPPO-

CAMPUS

Mesencephalic glioepithelium/ependyma

Diencephalic (hypothalamic)

glioepithelium/ependyma

Diencephalic (hypothalamic)

glioepithelium/ependyma

PLATE 138B