The Human Brain During the Third Trimester

Alvear

glioepithelium

Alve ar

glioepithelium

Amygdaloid

glioepithelium/ependyma

Amygdaloid

glioepithelium/ependyma

Uncinate

fasciculus?

Pa

ra

ce

n

tr

a

l

lo

b

u

le

White matter

Cortical plate

Layer I

HYPO-

THALAMUS

HYPO-

THALAMUS

AMYGDAMYGDALAALA

BASAL

GANGLIA

BA SAL

GANGLIA

TTe mporal lobeemporal lobe

Lateral

fissure

Central

sulcus

I

n

te

r

n

a

l

c

a

p

su

le

(^) (
c
e
n
tr
a
l/
p
o
st
e
r
io
r
(^) l
im
b
)
I
n
te
r
n
a
l
c
a
p
su
le
(^) (
c
e
n
tr
a
l/
p
o
st
e
r
io
r
(^) l
im
b
)
PutamenPutamen
Inferior temporal
gyrus
Inferior temporal
gyrus
Post-
central
gyrus
Po st-
central
gyrus
Precentral
gyrus
Precentral
gyrus
Callosal
glioepithelium
Lateral migratory stream
(infiltrates claustrum and
penetrates insular cortex)
Lateral migratory stream
(infiltrates claustrum and
penetrates insular cortex)
Lateral migratory stream
(extends to paracentral cortex)
Lateral migratory stream
(extends to paracentral cortex)
Lateral migratory stream
(extends to amygdala)
Lateral migratory stream
(extends to amygdala)
Lateral migratory stream
(extends to temporal neocortex)
Lateral migratory stream
Ventral (extends to temporal neocortex)
striatum
Ve ntral
striatum
Interhemispheric
fissure
Induseum
griseum
Tanycyte
ependyma
Tanycyte
ependyma
Lateral
tuberal
nucleus
D
or
so
m
ed
ia
l
an
d
(^) v
en
tr
om
ed
ia
l
n
uc
le
a
r
co
n
ti
nu
u
m
?
D
or
so
m
ed
ia
l
an
d
(^) v
en
tr
om
ed
ia
l
n
uc
le
a
r
co
n
ti
nu
u
m
?
Antero-
ventral
nucleus
Antero-
ventra l
nucleus
Ant
ero

• 
  

me

dia

l

nuc

leus

Ant

ero

• 
  

me

dia

l

nuc

leus

P

eri

v

entricular nuclei

P

eriventricular nuclei

Arcuate

nucleus

Arcuate

nucleus

G

lo

b

u

s^

p

a

llid

u

s

(in

te

rn

a

l

se

g

m

e

n

t)

G

lo

b

u

s^

p

a

llid

u

s

(in

te

rn

a

l

s

eg

m

e

n

t)

G

lo

b

us pallidus

(exter

nal segm

ent)

G

lo

bu

s pallidus

(exter

nal segm

ent)

Cave of the

septum

Cave of th e

septum

Uncinate

fasciculus?

I

n

s

u

al

r

g

y

r

u

s

I

n

s

u

al

r

g

y

r

u

s

C

al

u

s

tr

u

m

C

al

u

s

tr

u

m

Superior temporal

gyrus

Superior temporal

gyrus

Middle temporal

gyrus

Middle temporal

gyrus Central InterIntercalated massescalated masses

nucleus

Central

nucleus

Basal

nucleus

Basal

nucleus

Lateral

nucleus

Lateral

nucleus

Abnormal

hemorrhage in the

germinal matrix

Abnormal

hemorrhage in the

germinal matrix

FFornixornix

Fo

rn

ix

Fo

rn

ix

A

n

te

rio

r

co

m

m

is

su

re

A

n

te

rio

r

co

m

m

is

su

re

CCoorrppuussccaalllloossuumm((bbooddyy))

Optic

tract

Optic

tract

E

x

t

e

r

n

a

l

c

a

p

s

u

el

E

x

t

e

r

n

a

l

c

a

p

s

u

el

Subfornical

organ

Subfornical

organ

Third

ventricl e

Third

ventricle

Lateral ve ntricle

Medial

forebrain

bundle

Medial

forebrai n

bundle

Ventral

anterior

nucleus

Ve ntral

anterior

nucleus

M

e

d

u

ll

ar

y

la

m

in

a

M

e

d

u

ll

ar

y

la

m

in

a

Choroid

plexus

Choroid

plexus

VENTRAL

COMPLE

X

VENTRAL

COMPLE

X

A

N

T

ER

IO

R

C

O

M

PL

EX

A

N

T

ER

IO

R

C

O

M

PL

EX

P

E

R

IV

E

N

T

R

IC

U

L

A

R

C

O

M

P

L

E

X

P

E

R

IV

E

N

T

R

IC

U

L

A

R

C

O

M

P

L

E

XTHALAMUSTHALAMUS

R

et

ic

u

la

r

n

uc

le

us

R

et

ic

u

la

r

n

uc

le

us

R

E

T

IC

U

L

A

R

B

E

L

T

R

E

T

IC

U

L

A

R

B

E

L

T

Amygdalo-

hippocampal

area

Amygdalo-

hippocampal

area

FrFrontal lobeontal lobe

PParietal lobearietal lobe

Pa

ra

ce

n

tr

a

l

lo

b

u

le

CeCerre bral peduncleebral peduncle

Forel's

fields

Fo rel's

fields

An

sal

entic

ularis?

An

sal

entic

ularis?

C

ort

icaln

Cor uclei

ticaln

uclei

M

am

m

ilo

• th
  al
  am
  ic
  tr
  ac
  t

M

am

m

ilo

• th
  al
  am
  ic
  tr
  ac
  t
  Pa
  ra
  ce
  n
  tr
  al
  n
  uc
  le
  us
  ?

Pa

ra

ce

n

tr

al

n

uc

le

us

?

Reuniens

nucleus?

Reuniens

nucleus?

Massa

intermedia

Massa

intermedia

C

E

N

T

R

A

L

C

O

M

P

L

E

X

C

E

N

T

R

A

L

C

O

M

P

L

E

X

St

ri

a

m

ed

ull

ari

s

St

ri

a

m

ed

ull

ari

s

HippocampusHippocampus

Lateral

ventricle

Cingulum

Cingulate

gyrus

Cingulate

gyrus

Fornical

glioepithelium

Fo rnical

glioepithelium

Subpial granular layer

Fo

ra

m

en

of

M

on

ro

Pa rahippocampal

neuroepithelium

and subventricular zone

Pa rahippocampal

stratified transitional field

Temporal neuroepithelium

and subventricular zone

Te mporal neuroepithelium

and subventricular zone

Temporal stratified

transitional field

Te mporal stratified

transitional field

Stria

terminalis

Stria

terminalis

Germinal and transitional structures in italics

Fusiform

gyrus

Fusiform

gyrus Parahippocampal

gyrus

Parahippocampal

gyrus

Posterior striatal neuroepithelium

and subventricular zone

Po sterior striatal neuroepithelium

and subventricular zone

Strionuclear glioepitheliuStrionuclear glioepitheliumm

Hypothalamic

glioepithelium/

ependyma

Hypothalamic

glioepithelium/

ependyma

Thalamic

glioepithelium/

ependyma

Thalamic

glioepithelium/

ependyma

Entorhinal

cortex

Caudate

(tail)

Caudate

(tail)

Fr ontal/paracentral neuroepithelium

and subventricular zone Fr ontal/paracentral

stratified transitional field

PLATE 179B