The Human Brain During the Third Trimester

Central

nucleus

B

A

S

A

L

G

A

N

G

L

IA

Choroid plexus

HIPPOCAMPUHIPPOCAMPUSS

Fimbria/fornix

Subiculum

Dentate gyrus

Ammon's horn

CCaauuddaatete (h (heeaadd))

Putam

en

Putam

en

Caudate (tail)Caudate (tail)

C

la

us

tr

um

C

la

us

tr

um

Lateral ventricle

Temporal

lobe

Te mporal

lobe

Frontal

lobe

Frontal

lobe

Lateral migratory stream

(infiltrating the claustrum and entering

the insular cortex and temporal cortex)

In

su

la

r^

gy

ru

s

In

su

la

r^

gy

ru

s

Lateral

fissure Superior temporal

gyrus

Superior temporal

gyrus

Middle temporal gyrusMiddle temporal gyrus

Stria

terminalis

Stria

terminalis

Layer I

Subpial granular layerSubpial granular layer

Cortical plate

White matter

Inferior frontal gyrus

Mammillo-

thalamic tract?

Mammillo-

thalamic tract?

Third vThird ventricleentricle

Diencephalic

(hypothalamic)

glioepithelium/

ependyma

Diencephalic

(hypothalamic)

glioepithelium/

ependyma

Mesencephalic

glioepithelium/

ependyma

Mesencephalic

glioepithelium/

ependyma

Subcommissural

orga n

Central

nucleus

Lingula

(I-II)

Lingula

(I-II)

Centralis

(III)

Centralis

(III)

Culmen

(IV-V)

Culmen

(IV-V)

Primary

fissure

Primary

fissure

Declive

(VI)

Declive

(VI)

Folium

(VIIa)

Fo lium

(VIIa)

Simplex lobule

(HVI)

Simplex lobu le

(HVI)

Lateral lemniscus

Brachium of the

inferior colliculus

TEGMENTUMTEGMENTUM

colliculuInferior

s

colliculuInferior

s

Tenia tecta

(ventral)

Tenia tecta

(ventral)

FFornixornix

Diagonal band of Broca

(vertical limb)

Diagonal band of Broca

(vertical limb)

Diagonal band

of Broca (hori-

zontal limb)

Diagonal band

of Broca (hori-

zontal limb)

Basal nucleus

of Meynert?

Basal nucleus

of Meynert?

Median preoptic

nucleus

Median preoptic

nucleus

Medial preoptic

nucleus

Medial preoptic

nucleus

Lateral Lateral ventriclventriclee

Nucleus

accumbens

Nucleus

accumbens

Ventral

striatum

Ve ntral

striatum

Corp

us (^) cal
(r losum
ostrum
)
Corp
us (^) cal
(r losum
ostrum
)
Subcallosal arSubcallosal areaea
Paraventricular
nucleus
Paraventricular
nucleus
Central grayCentral gray

A

n

te

rio

r^

c

om

m

issu

re

A

n

te

rio

r^

c

om

m

issu

re

Ansa

lenticularis?

Ansa

lenticularis?

Cerebral

aqueduct

Cere bral

aqueduct

HYPOHYPOTHALAMUSTHALAMUS

CEREBELLAR CEREBELLAR VERMISVERMIS

CEREBELLAR

HEMISPHERE

CEREBELLAR

HEMISPHERE

Parahippocampal

gyrus

Parahippocampal

gyrus

Subgranular zone

Subgranular zone

Subgranular zoneExternal germinal layer

Ext

erna

l cap

sule

Ext

erna

l cap

sule

Inte

rna

l ca

psu

le?

(Ant

erior

limb

)

Inte

rna

l ca

psu

le?

(Ant

erior

limb

)

Internal capsule (posterior limb)

B

A

S

A

L

G

A

N

G

L

IA

S

U

B

S

T

A

N

T

IA

IN

N

O

M

IN

A

T

A

S

U

B

S

T

A

N

T

IA

IN

N

O

M

IN

A

T

A

PREOPTIC

AREA

PREOPTIC

AREA

Med

ial

fore

bra

in

bun

dle?

Med

ial

fore

bra

in

bun

dle?

Su

b

th

ala

m

ic

nu

cle

us

Su

b

th

ala

m

ic

nu

cle

us

Red

nucleus

Red

nucleus

Inter-

peduncular

nucleus?

Inter-

peduncular

nucleus?

Habenulo-

interpeduncular

tract

Habenulo-

interpeduncular

tract

Dorsal tegmental

nucleus?

Dorsal tegmental

nucleus?

Oculomotor

nuclear complex

Oculomotor

nuclear complex

C

e

re

b

ra

lp

ed

un

cle

C

e

re

b

ra

lp

ed

un

cle

Optic

tr

act

Optic

tr

act

Supra-

mammillary

area

Supra-

mammillary

area

Dorsomedial

nucleus?

Dorsomedial

nucleus?

Lateral prLateral preoptic and eoptic and hhypothalamic arypothalamic areaeass

Accumbent neuroepithelium

(intermingled with the

rostral migratory stream)

Accumbent neuroepithelium

(intermingled with the

rostral migratory stream)

Rostral migratory stream

(source area)

Rostral migratory stream

(source area)

Frontal neuroepithelium

and subventricular zone

Fr ontal neuroepithelium

and subventricular zone

Frontal stratified

transitional field

Fr ontal stratified

transitional field

Parahippocampal neuroepithe-

lium and subventricular zone

Pa rahippocampal neuroepithe-

lium and subventricular zone

Parahippocampal

stratified transitional field

Pa rahippocampal

stratified transitional field

Te mporal neuroepithelium and subventricular zone

Te mporal stratified transitional field

Stem cells of

choroid plexus?

Stem cells of

choroid plexus?

Stem cells of

choroid plexus?

Stem cells of

choroid plexus?

Germinal and transitional

structures in italics

Germinal and transitional

structures in italics

Po sterior striatal neuroepithelium

and subventricular zone

MIDBRAIMIDBRAINN

TECTUMTECTUM

Stria terminalisStria terminalis

GlioepitheliuGlioepitheliumm

Alve ar

glioepithelium

Fornical

glioepithelium

Fo rnical

glioepithelium

Ansiform

lobule

(Crus I HVIIA)

Ansiform

lobu le

(Crus I HVIIA)

PLATE 234B