HUMAN BIOLOGY

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patellar tendon

motor
neuron

reflex arc

extensor muscle of knee
(quadriceps femoris)
muscle
spindle

The “knee jerk” patellar reflex diagrammed in Figure 13.27 is a
familiar example of a reflex arc. A doctor will often use a small rubber-
tipped instrument to test for this reflex, but you can easily trigger it yourself
just by tapping the base of one of your kneecaps (the patella) with a knuckle.
The reflex occurs when stretch receptors in a tendon attached to the patella
are activated, leading to a contraction of the quadriceps femoris, the exten-
sor muscle of the knee.
Try tapping the base of one of your kneecaps (not too forcefully) and see
if you can elicit the patellar reflex. Then write a short paragraph describing
the path of the reflex arc, including the location and kind of neurons that inte-
grated the sensory information and ordered a muscle response.

Figure 13.27 a reflex arc operates in the patellar reflex. (© Cengage Learning)

262 Chapter 13

suMMary


section 13.1 The nervous system
detects, processes, and responds to stimuli.
Sensory neurons respond directly to external
or internal stimuli. Interneurons in the brain
and spinal cord receive sensory signals,
process them, and then send outgoing signals that influence
other neurons. Motor neurons relay messages away from the
brain and spinal cord to muscles or glands. Neuroglia provide
various forms of physical or chemical support for neurons.
Neurons have extensions called axons and dendrites. Axons
carry outgoing signals, and dendrites receive them. A resting
neuron has a steady voltage difference across its plasma
membrane. This difference is called the resting membrane
potential.
A neuron maintains concentration gradients of various
ions, notably sodium and potassium, across the membrane.
Changes in this difference allow a neuron to send signals
(nerve impulses).
section 13.2 When the voltage
difference across the membrane exceeds a
threshold level, gated sodium channels in
the membrane open and close rapidly and
suddenly reverse the voltage difference.
This reversal is a nerve impulse, or action

potential. A sodium–potassium pump restores ion gradients
after an action potential fires. Action potentials propagate
away from the point of stimulation.
section 13.3 Action potentials selfpro-
pagate along the neuron membrane until
they reach a synapse with another neuron,
muscle, or gland. The presynaptic cell
releases a neurotransmitter into the synapse.
The neurotransmitter excites or inhibits the
receiving (postsynaptic) cell. Synaptic integra-
tion sums up the various signals acting on a neuron. Neuro-
modulators boost or reduce the effects of neurotransmitters.
section 13.4 Nerves consist of the long
axons of motor neurons, sensory neurons, or
both. A myelin sheath formed by Schwann
cells insulates each axon, so that action
potentials propagate along it much more
rapidly. Nerve pathways extend from neurons in one body
region to neurons or effectors in different regions.
A reflex is a simple, stereotyped movement in response to
a stimulus. In the simplest reflexes, sensory neurons directly
signal motor neurons that act on muscle cells. In more complex
reflexes, interneurons coordinate and refine the responses.

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