HUMAN BIOLOGY

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312 Chapter 16

how sperm Form


Sperm form in seminiferous tubules


Packed inside each of a male’s testes are 125 meters—over
400 feet—of seminiferous tubules. As many as thirty
wedge-shaped lobes divide the inside of a testis and
each lobe holds two or three coiled tubules (Figure 16.6A
a nd 16.6B).
In the walls of seminiferous tubules are cells called
spermatogonia (singular: spermatogonium; Figure 16.6C).
Spermatogonia are the starting
point of spermatogenesis, the
formation of sperm. This pro-
cess requires several rounds of
cell division, including a type
called mitosis and a type called
meiosis. You’ll read more about
cell division in Chapter 18; here
the main thing to keep in mind
is that meiosis is necessary to
form sperm and eggs.
Spermatogonia develop into primary spermatocytes,
which become secondary spermatocytes after a first round
of meiosis (meiosis I). A second round (meiosis II) forms
spermatids. The spermatids develop into spermatozoa, or
simply sperm, the male gametes. The “tail” of each sperm,
a flagellum, forms at the end of the process, which takes
9 to 10 weeks. Meanwhile, the developing cells receive

n In his reproductive years, a male continually produces
sperm, which develop in a series of steps controlled by
hormones.
n Links to Flagella 3.9, Hormones from the hypothalamus and
pituitary 15.3

seminal
vesicle

prostate
gland
bulbourethral
gland

urethra

epididymis

vas
deferens

penis

testis

seminiferous
tubule


primary
spermatocyte

spermatogonium
(diploid)
Leydig cells
between tubules

wall of
seminiferous
tubule Sertoli cell secondary spermatocyte

early
spermatids
late spermatid

immature sperm
(haploid)

mitosis meiosis I meiosis II lumen

Figure 16.6 Animated! Sperm form inside seminiferous tubules in the testes. A The male reproductive tract from behind. B Cells in
three neighboring seminiferous tubules. Leydig cells in spaces between tubules make testosterone. C How sperm form, starting with a
diploid germ cell. (A: © Cengage Learning; B: © Ed Reschke/Peter Arnold; C: © Cengage Learning)

A

B

C

16.4


seminiferous tubules
Coiled tubules in the testes
that contain the cells from
which sperm develop.
sperm Male gametes.
spermatogenesis
Process in which sperm
form.

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