HUMAN BIOLOGY

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372 Chapter 18


CritiCaL thinKing



  1. Normally you can’t inherit both copies of a homologous
    chromosome from the same parent. Why? Assuming that
    no crossing over has occurred, how likely is it that one of
    your non-sex chromosomes is an exact copy of the same
    chromosome your maternal grandmother had? Explain
    your answer.

  2. Suppose you have a way of measuring the amount
    of DNA in a single cell during the cell cycle. You first
    measure the amount during the G1 phase. At what points
    during the remainder of the cycle would you predict
    changes in the amount of DNA per cell?

  3. Adam’s maternal and paternal chromosomes have
    alternate forms of a gene that influences whether a
    person is right-handed or left-handed. One form says
    “right” and its partner says “left.” Visualize one of
    Adam’s spermatogonia, in which chromosomes are being
    duplicated prior to meiosis. Visualize what happens to the
    chromosomes during anaphase I and II. (It might help to
    use toothpicks as models of the sister chromatids of each
    chromosome.) What fraction of Adam’s sperm will carry
    the gene for right-handedness? For left-handedness?


In cancer, cells divide abnormally
because the usual controls over mitosis
are lost. Researchers working with can-
cerous cells have identified how nearly
600 different genes affect mitosis in
those cells. The next step is to discover
how changes in such “mitosis” genes
affect healthy cells. This information
may provide much better understanding of exactly how mitosis
goes awry as cancer gets started—knowledge that could help
lead to more effective treatment for some cancers.

your Future


© Cengage Learning


  1. Fresh out of college, Maria has her first job teaching
    school. When she goes for a pre-employment chest X-ray
    required by the school district, the technician places a
    lead-lined apron over her abdomen but not over any other
    part of Maria’s body. The apron prevents electromagnetic
    radiation from penetrating into the protected body area.
    What cells is the lead shield designed to protect, and why?


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