Stem Cell Processing (Stem Cells in Clinical Applications)

48 Table 2.6 Clinical trials using MSC s for intra-articular injection of cells Study name; clinicaltrials. gov identifi er Cell ...

49 Table 2.6 (continued) Study name; clinicaltrials. gov identifi er Cell type and source Indication Study phase; design Allogen ...

50 Table 2.6 (continued) Study name; clinicaltrials. gov identifi er Cell type and source Indication Study phase; design Allogen ...

51 2.3.2.2 Cardiovascular Diseases Today, more than 40 clinical trials are l isted with a majority of bone marrow, Wharton’s jel ...

52 resulted in the induction of clinical remission and improvements in serological markers of organ dysfunction (Liang et al. 20 ...

53 signifi cantly increased the survival rates in acute chronic liver failure patients (Shi et al. 2012 ). In summary, these dat ...

54 2.3.2.6 MSCs in Acute Brain Injury: Stroke In recent years, clinical trials usin g MSC in stroke have increased dramatically. ...

55 (de la Fuente et al. 2010 ; Garcia et al. 2010 ; Rubio et al. 2005 ; Torsvik et al. 2010 ). Roemeling-van Rhijn et al. ( 2013 ...

56 Table 2.7 List of completed clinical trials us ing ex vivo expanded MSCs Clinical trial no. Source of MSCS Serum supplement D ...

57 NCT00683722 Allo-BM – Coronary obstructive pulmonary disorder 100 × 10 6 cells Intravenous II Randomized, safety/effi cacy st ...

58 References Ab Kadir R, Zainal Ariffi n SH, Megat Abdul Wahab R, Kermani S, Senafi S (2012) Characterization of mononucleated ...

59 Castren E, Sillat T, Oja S, Noro A, Laitinen A, Konttinen YT, Lehenkari P, Hukkanen M, Korhonen M (2015) Osteogenic different ...

60 Dulamea A (2015) Mesenchymal stem cells in multiple sclerosis—translation to clinical trials. J Med Life 8:24–27 El-Kheir WA, ...

61 kidney injury with allogeneic mesenchymal stem cells in patients who require on-pump cardiac surgery. Cell Ther Transplant 1: ...

62 Ibrahim AM, Elgharabawi NM, Makhlouf MM, Ibrahim OY (2015) Chondrogenic differentiation of human umbilical cord blood-derived ...

63 Lee JW, Lee SH, Youn YJ, Ahn MS, Kim JY, Yoo BS, Yoon J, Kwon W, Hong IS, Lee K et al (2014) A randomized, open-label, multic ...

64 Matthay MA, Goolaerts A, Howard JP, Lee JW (2010) Mesenchymal stem cells for acute lung injury: preclinical evidence. Crit Ca ...

65 Pak J (2011) Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteo- arthritis with autologous ad ...

66 Rubio D, Garcia-Castro J, Martin MC, de la Fuente R, Cigudosa JC, Lloyd AC, Bernad A (2005) Spontaneous human adult stem cell ...

67 Tang WP, Akahoshi T, Piao JS, Narahara S, Murata M, Kawano T, Hamano N, Ikeda T, Hashizume M (2015) Splenectomy enhances the ...