92
pluripotent factors, culture systems without animal cells or contamination, and
iPSC production according to GMP standards. These improvements in iPSC tech-
nology will signifi cantly contribute not only to drug discovery and drug screening
but also to regenerative medicine.
Acknowledgments This work was funded by grant number: 106-YS.06-2013.37 (Nafosted,
Viet Nam).
References
Aasen T, Izpisua Belmonte JC (2010) Isolation and cultivation of human keratinocytes from skin
or plucked hair for the generation of induced pluripotent stem cells. Nat Protoc 5:371–382
Acimovic I, Vilotic A, Pesl M, Lacampagne A, Dvorak P, Rotrekl V, Meli AC (2014) Human plu-
ripotent stem cell-derived cardiomyocytes as research and therapeutic tools. BioMed Res Int
2014:512831
Ambasudhan R, Talantova M, Coleman R, Yuan X, Zhu S, Lipton SA, Ding S (2011) Direct repro-
gramming of adult human fi broblasts to functional neurons under defi ned conditions. Cell Stem
Cell 9(9):113–118
Anokye-Danso F, Trivedi CM, Juhr D, Gupta M, Cui Z, Tian Y, Zhang Y, Yang W, Gruber PJ,
Epstein JA et al (2011) Highly effi cient miRNA-mediated reprogramming of mouse and human
somatic cells to pluripotency. Cell Stem Cell 8:376–388
Ausubel LJ, Lopez PM, Couture LA (2011) GMP scale-up and banking of pluripotent stem cells
for cellular therapy applications. Methods Mol Biol 767:147–159
Ban H, Nishishita N, Fusaki N, Tabata T, Saeki K, Shikamura M, Takada N, Inoue M, Hasegawa
M, Kawamata S et al (2011) Effi cient generation of transgene-free human induced pluripotent
stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci USA
108:14234–14239
Bergstrom R, Strom S, Holm F, Feki A, Hovatta O (2011) Xeno-free culture of human pluripotent
stem cells. Methods Mol Biol 767:125–136
Blelloch R, Venere M, Yen J, Ramalho-Santos M (2007) Generation of induced pluripotent stem
cells in the absence of drug selection. Cell Stem Cell 1:245–247
Brambrink T, Foreman R, Welstead GG, Lengner CJ, Wernig M, Suh H, Jaenisch R (2008)
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic
cells. Cell Stem Cell 2:151–159
Brown ME, Rondon E, Rajesh D, Mack A, Lewis R, Feng X, Zitur LJ, Learish RD, Nuwaysir EF
(2010) Derivation of induced pluripotent stem cells from human peripheral blood T lympho-
cytes. PLoS One 5, e11373
Freund C, Davis RP, Gkatzis K, Ward-Van Oostwaard D, Mummery CL (2010) The fi rst reported
generation of human induced pluripotent stem cells (iPS cells) and iPS cell-derived cardiomyo-
cytes in the Netherlands. Neth Heart J 18:51–54
Mummery C, Ward-van Oostwaard D, Doevendans P et al (2003) Differentiation of human embry-
onic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells.
Circulation 107:2733–2740
Caiazzo M, Dell’Anno MT, Dvoretskova E, Lazarevic D, Taverna S, Leo D, Sotnikova TD,
Menegon A, Roncaglia P, Colciago G et al (2011) Direct generation of functional dopaminer-
gic neurons from mouse and human fi broblasts. Nature (Lond) 476:224–227
Carver-Moore K, Broxmeyer HE, Luoh SM, Cooper S, Peng J, Burstein SA, Moore MW, de
Sauvage FJ (1996) Low levels of erythroid and myeloid progenitors in thrombopoietin- and
c-mpl-defi cient mice. Blood 88:803–808
P.V. Pham et al.