281De Robertis EM (2006) Spemann’s organizer and self-regulation in amphibian embryos. Nat Rev
Mol Cell Biol 7:296–302. doi:10.1038/nrm1855
De Robertis EM, Sasai Y (1996) A common plan for dorsoventral patterning in Bilateria. Nature
380:37–40. doi:10.1038/380037a0
De Vries WN, Evsikov AV, Haac BE et al (2004) Maternal beta-catenin and E-cadherin in mouse
development. Development 131:4435–4445. doi:10.1242/dev.01316
Deans MR, Antic D, Suyama K et al (2007) Asymmetric distribution of Prickle-like 2 reveals
an early underlying polarization of vestibular sensory epithelia in the inner ear. J Neurosci
27:3139–3147. doi:10.1523/JNEUROSCI.5151-06.2007
Delaune E, Lemaire P, Kodjabachian L (2005) Neural induction in Xenopus requires early FGF
signalling in addition to BMP inhibition. Development 132:299–310. doi:10.1242/dev.01582
Dick A, Hild M, Bauer H, Imai Y, Maifeld H, Schier AF, Talbot WS, Bouwmeester T,
Hammerschmidt M (2000) Essential role of Bmp7 (snailhouse) and its prodomain in dorsoven-
tral patterning of the zebrafish embryo. Development 127:343–354
Ding J, Yang L, Yan YT et al (1998) Cripto is required for correct orientation of the anterior-
posterior axis in the mouse embryo. Nature 395:702–707. doi:10.1038/27215
Dirksen ML, Jamrich M (1992) A novel, activin-inducible, blastopore lip-specific gene of Xenopus
laevis contains a fork head DNA-binding domain. Genes Dev 6:599–608
Djiane A, Riou J, Umbhauer M et al (2000) Role of frizzled 7 in the regulation of convergent
extension movements during gastrulation in Xenopus laevis. Development 127:3091–3100
Dobrowolski R, De Robertis EM (2012) Endocytic control of growth factor signalling: multive-
sicular bodies as signalling organelles. Nat Rev Mol Cell Biol 13:53–60. doi:10.1038/nrm3244
Doi JY, Niigaki H, Sone K et al (2000) Distribution of dorsal-forming activity in precleavage
embryos of the Japanese newt, Cynops pyrrhogaster: effects of deletion of vegetal cytoplasm,
UV irradiation, and lithium treatment. Dev Biol 223:154–168. doi:10.1006/dbio.2000.9735
Domingos PM, Itasaki N, Jones CM et al (2001) The Wnt/beta-catenin pathway posteriorizes neu-
ral tissue in Xenopus by an indirect mechanism requiring FGF signalling. Dev Biol 239:148–
- doi:10.1006/dbio.2001.0431
Dorsky RI, Itoh M, Moon RT, Chitnis A (2003) Two tcf3 genes cooperate to pattern the zebrafish
brain. Development 130:1937–1947
Dougan ST, Warga RM, Kane DA et al (2003) The role of the zebrafish nodal-related genes squint
and cyclops in patterning of mesendoderm. Development 130:1837–1851
Du SJ, Purcell SM, Christian JL et al (1995) Identification of distinct classes and functional
domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos.
Mol Cell Biol 15:2625–2634
Dufort D, Schwartz L, Harpal K, Rossant J (1998) The transcription factor HNF3beta is required in
visceral endoderm for normal primitive streak morphogenesis. Development 125:3015–3025
Dyson S, Gurdon JB (1998) The interpretation of position in a morphogen gradient as revealed by
occupancy of activin receptors. Cell 93:557–568
Egger-Adam D, Katanaev VL (2010) The trimeric G protein Go inflicts a double impact on axin in
the Wnt/frizzled signaling pathway. Dev Dyn 239:168–183. doi:10.1002/dvdy.22060
Elinson R, Pasceri P (1989) Two UV-sensitive targets in dorsoanterior specification of frog
embryos. Development 106:511–518
Elinson RP (1983) Cytoplasmic phases in the first cell cycle of the activated frog egg. Dev Biol
100:440–451
Elinson RP, del Pino EM (2011) Developmental diversity of amphibians. WIREs Dev Biol 1:345– - doi:10.1002/wdev.23
Elinson RP, Holowacz T (1995) Specifying the dorsoanterior axis in frogs: 70 years since Spemann
and Mangold. Curr Top Dev Biol 30:253–285
Elinson RP, Kezmoh L (2010) Molecular Haeckel. Dev Dyn 239:1905–1918. doi:10.1002/
dvdy.22337
Elinson RP, Rowning B (1988) A transient array of parallel microtubules in frog eggs: potential
tracks for a cytoplasmic rotation that specifies the dorso-ventral axis. Dev Biol 128:185–197
6 Vertebrate Axial Patterning: From Egg to Asymmetry