543Interferon (IFN) pathway, 498
Interpolar microtubules, 120
Intracisternal A particle (IAP), 516
Intrinsically Disordered Proteins Theory,
195–197
Isobaric tags for relative and absolute
quantitation (iTRAQ) analysis, 513
K
Koller’s sickle (KS)
description, 316
gastrulation, vertebrate species, 316, 317
KS. See Koller’s sickle (KS)
L
Last cell standing model, 421
Late vegetal mRNA localization pathway,
188, 189
M
MacroH2A, 520
Mammal(s), 422, 423
epigenetic reprogramming, 425–426
germ cell induction domains, 423–424
germ cell specification genes
Blimp1, 422, 423
Tcfap2c/AP2g, 423
pluripotent gene expression, 424, 425
Mammalian embryo, 318
compaction, 153–156
polarization, 223, 224
Mammalian fate map, 327
Mammalian oocytes, 493
Maternal chromatin modifications, OET,
519–520
Maternal factors accumulation, 493
Maternal mRNAs, 54
biological functions, 53–54
germ layers and embryonic asymmetries,
54, 55
Maternal protein degradation. See Protein
degradation
Maternal ribosomes, 508–509
Maternal RNA clearance, 496–508
degradation, 495
degradation, mRNAs (see Messenger
RNAs (mRNAs) degradation, OET)
elimination rRNA, 508–509
elimination, small RNAs (see Maternal
small RNAs)
mammalian model, 495
maternal ribosomes, 508–509
nonmammalian model, 495
Maternal small RNAs
and clearance, 500
microRNAs, 496–498
noncoding, 496
pathways, 496
piRNAs, 499–500
siRNAs from RNAi pathway, 498–499
Maternal-to-zygotic transition (MZT), 490
Maturation-promoting factor (MPF), 85, 195
MBT. See Midblastula transition (MBT)
Meiotic maturation
ARE and CPE, 506
bioinformatics analysis, 506
CCR4 deadenylase, 505
cis-acting sequence/structural motifs, 505
decapping, 505
mouse transcriptome changes, 506
mRNA stability to instability, 505
MSY2, 505, 506
oocyte stockpiling resources, 505
passive maternal mRNA elimination,
503–504
poly(A) RNA reduction, 505
polyadenylated RNA, 505
ribosomal proteins, 505
trans-acting factors, 506
in Xenopus oocytes, 512
MEK/MAP kinase (MAPK) signalling, 102
Meroblastic cleavage, 119
Mesoderm inducing signals, 348–352
nodal-related gene expression
chicken, 350–351
mouse, 348–349
Xenopus, 351
Zebrafish, 351–352
TGF-β and Fgf, 347–348
Mesoderm induction, 419
Messenger RNAs (mRNAs) degradation, OET
Dormant maternal mRNAs, 501
elimination, meiotic maturation, 503–504
endonucleolytic activity, 501
eukaryotic, 500
exonucleolytic, 501
fertilization, 506–507
mechanisms, 500
meiotic maturation, 504–506
mouse OET, 501, 502
OET transitions, 501
phases, developmental transitions, 501
poly(A) RNA, 502–503Index