Novel Chemical Tools to Study Ion Channel Biology (Advances in Experimental Medicine and Biology)

(sharon) #1

46 M. H. Akabas


Cha A, Bezanilla F (1997) Characterizing voltage-dependent conformational changes in the Shak-
er K+ channel with fluorescence. Neuron 19(5):1127–1140
Cha A, Bezanilla F (1998) Structural implications of fluorescence quenching in the Shaker K+
channel. J Gen Physiol 112(4):391–408
Cha A, Zerangue N, Kavanaugh M, Bezanilla F (1998) Fluorescence techniques for studying cloned
channels and transporters expressed in Xenopus oocytes. Methods Enzymol 296:566–578
Cha A, Snyder GE, Selvin PR, Bezanilla F (1999) Atomic scale movement of the voltage-sens-
ing region in a potassium channel measured via spectroscopy. Nature 402(6763):809–813.
doi:10.1038/45552
Chanda B, Asamoah OK, Bezanilla F (2004) Coupling interactions between voltage sensors of
the sodium channel as revealed by site-specific measurements. J Gen Physiol 123(3):217–230.
doi:10.1085/jgp.200308971
Chang Y, Weiss DS (2002) Site-specific fluorescence reveals distinct structural changes with
GABA receptor activation and antagonism. Nat Neurosci 5(11):1163–1168. doi:10.1038/
nn926 nn926 [pii]
Chen JG, Rudnick G (2000) Permeation and gating residues in serotonin transporter. Proc Natl
Acad Sci U S A 97(3):1044–1049
Cheung M, Akabas MH (1996) Identification of cystic fibrosis transmembrane conductance regu-
lator channel-lining residues in and flanking the M6 membrane-spanning segment. Biophys J
70(6):2688–2695
Cleland WW (1964) Dithiothreitol, a new protective reagents for SH groups. Biochemistry 3:480–482
Contreras JE, Srikumar D, Holmgren M (2008) Gating at the selectivity filter in cyclic nucleotide-
gated channels. Proc Natl Acad Sci U S A 105(9):3310–3314. doi:10.1073/pnas.0709809105
Corringer PJ, Bertrand S, Galzi JL, Devillers-Thiery A, Changeux JP, Bertrand D (1999) Muta-
tional analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor.
Neuron 22 (4):831–843. doi:S0896-6273(00)80741-2 [pii]
Crawhall JC, Segal S (1966) Dithiothreitol in the study of cysteine transport. Biochim Biophys
Acta 121(1):215–217
Cross TA, Sharma M, Yi M, Zhou HX (2011) Influence of solubilizing environments on mem-
brane protein structures. Trends Biochem Sci 36(2):117–125. doi:S0968-0004(10)00137-4
[pii] 10.1016/j.tibs.2010.07.005
Cymes GD, Grosman C (2012) The unanticipated complexity of the selectivity-filter glutamates of
nicotinic receptors. Nat Chem Biol 8(12):975–981. doi:10.1038/nchembio.1092
Cymes GD, Ni Y, Grosman C (2005) Probing ion-channel pores one proton at a time. Nature
438(7070):975–980. doi:nature04293 [pii] 10.1038/nature04293
Czajkowski C, Karlin A (1991) Agonist binding site of Torpedo electric tissue nicotinic acetyl-
choline receptor. A negatively charged region of the delta subunit within 0.9 nm of the alpha
subunit binding site disulfide. J Biol Chem 266(33):22603–22612
Czajkowski C, Kaufmann C, Karlin A (1993) Negatively charged amino acid residues in the nico-
tinic receptor delta subunit that contribute to the binding of acetylcholine. Proc Natl Acad Sci
U S A 90(13):6285–6289
Dahan DS, Dibas MI, Petersson EJ, Auyeung VC, Chanda B, Bezanilla F, Dougherty DA, Lester
HA (2004) A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects produc-
tive binding of agonist to the alpha delta site. Proc Natl Acad Sci U S A 101(27):10195–10200.
doi:10.1073/pnas.0301885101
Dennis M, Giraudat J, Kotzyba-Hibert F, Goeldner M, Hirth C, Chang JY, Lazure C, Chretien
M, Changeux JP (1988) Amino acids of the Torpedo marmorata acetylcholine receptor al-
pha subunit labeled by a photoaffinity ligand for the acetylcholine binding site. Biochemistry
27(7):2346–2357
Depuydt M, Messens J, Collet JF (2011) How proteins form disulfide bonds. Antioxid Redox
Signal 15(1):49–66. doi:10.1089/ars.2010.3575
Dickens F (1933) Interaction of halogenacetates and SH compounds: the reaction of halogenacetic
acids with glutathione and cysteine. The mechanism of iodoacetate poisoning of glyoxalase.
Biochem J 27(4):1141–1151

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