Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical, Part 1

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  1. Jain A, Lamark T, Sjøttem E et al (2010) p62/SQSTM1 is a target gene for transcription factor
    NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven
    gene transcription. J Biol Chem 285(29):22576–22591

  2. Pickering AM, Linder RA, Zhang H et  al (2012) Nrf2-dependent induction of proteasome
    and Pa28alphabeta regulator are required for adaptation to oxidative stress. J  Biol Chem
    287(13):10021–10031

  3. Cullinan SB, Gordan JD, Jin J et al (2004) The Keap1-BTB protein is an adaptor that bridges
    Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol Cell
    Biol 24(19):8477–8486

  4. Furukawa M, Xiong Y (2005) BTB protein Keap1 targets antioxidant transcription factor
    Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase. Mol Cell Biol 25(1):162–171

  5. Kobayashi A, Kang MI, Okawa H et al (2004) Oxidative stress sensor Keap1 functions as an
    adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol
    24(16):7130–7139

  6. Tong KI, Katoh Y, Kusunoki H et al (2006) Keap1 recruits Neh2 through binding to ETGE
    and DLG motifs: characterization of the two-site molecular recognition model. Mol Cell Biol
    26(8):2887–2900

  7. Rada P, Rojo AI, Chowdhry S et  al (2011) SCF/{beta}-TrCP promotes glycogen synthase
    kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent man-
    ner. Mol Cell Biol 31(6):1121–1133

  8. Cullinan SB, Diehl JA (2006) Coordination of ER and oxidative stress signaling: the PERK/
    Nrf2 signaling pathway. Int J Biochem Cell Biol 38(3):317–332

  9. Kensler TW, Wakabayashi N, Biswal S (2007) Cell survival responses to environmental
    stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 47:89–116

  10. Kwak MK, Itoh K, Yamamoto M et al (2002) Enhanced expression of the transcription factor
    Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences
    in the nrf2 promoter. Mol Cell Biol 22(9):2883–2892

  11. Narasimhan M, Hong J, Atieno N et al (2014) Nrf2 deficiency promotes apoptosis and impairs
    PAX7/MyoD expression in aging skeletal muscle cells. Free Radic Biol Med 71:402–414

  12. Narasimhan M, Mahimainathan L, Rathinam ML et  al (2011) Overexpression of Nrf2
    protects cerebral cortical neurons from ethanol-induced apoptotic death. Mol Pharmacol
    80(6):988–999

  13. Mukaigasa K, Nguyen LTP, Li L et al (2012) Genetic evidence of an evolutionarily conserved
    role for Nrf2 in the protection against oxidative stress. Mol Cell Biol 32(21):4455–4461

  14. Kunapuli S, Rosanio S, Schwarz ER (2006) “How do cardiomyocytes die?” apoptosis and
    autophagic cell death in cardiac myocytes. J Card Fail 12(5):381–391

  15. Hamacher-Brady A, Brady NR, Gottlieb RA (2006) The interplay between pro-death and
    pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets
    autophagy. Cardiovasc Drugs Ther 20(6):445–462

  16. Terman A, Gustafsson B, Brunk UT (2007) Autophagy, organelles and ageing. J  Pathol
    211(2):134–143

  17. Warabi E, Takabe W, Minami T et al (2007) Shear stress stabilizes NF-E2-related factor 2 and
    induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species. Free
    Radic Biol Med 42(2):260–269

  18. Tan Y, Ichikawa T, Li J et al (2011) Diabetic downregulation of Nrf2 activity via ERK con-
    tributes to oxidative stress-induced insulin resistance in cardiac cells in  vitro and in  vivo.
    Diabetes 60(2):625–633

  19. Suh JH, Shenvi SV, Dixon BM et al (2004) Decline in transcriptional activity of Nrf2 causes
    age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad
    Sci U S A 101(10):3381–3386

  20. Lewis KN, Mele J, Hornsby PJ et al (2012) Stress resistance in the naked mole-rat: the bare
    essentials - a mini-review. Gerontology 58(5):453–462


M. Narasimhan and N.-S. Rajasekaran
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