Stern JE, Sonner PM, Son SJ et al (2012) Exercise training normalizes an increased neuronal
excitability of NTS-projecting neurons of the hypothalamic paraventricular nucleus in hyper-
tensive rats. J Neurophysiol 107(10):2912–2921
Kishi T, Hirooka Y, Katsuki M et al (2012) Exercise training causes sympathoinhibition
through antioxidant effect in the rostral ventrolateral medulla of hypertensive rats. Clin Exp
Hypertens 34(4):278–283
Garciarena CD, Pinilla OA, Nolly MB et al (2009) Endurance training in the spontane-
ously hypertensive rat: conversion of pathological into physiological cardiac hypertrophy.
Hypertension 53(4):708–714
Agarwal D, Elks CM, Redd SD et al (2012) Chronic exercise preserves renal structure and
hemodynamics in spontaneously hypertensive rats. Antioxid Redox Signal 16(2):139–152
Folkow B (2004) Pathogenesis of structural vascular changes in hypertension. J Hypertens
22(6):1231–1233
Mulvany MJ (2012) Small artery remodelling in hypertension. Basic Clin Pharmacol Toxicol
110(1):49–55
Herrera VL, Decano JL, Giordano N et al (2014) Aortic and carotid arterial stiffness and epi-
genetic regulator gene expression changes precede blood pressure rise in stroke-prone Dahl
salt-sensitive hypertensive rats. PLoS One 9(9):e107888
Van Gorp AW, Schenau DS, Hoeks AP et al (2000) In spontaneously hypertensive rats altera-
tions in aortic wall properties precede development of hypertension. Am J Physiol Heart Circ
Physiol 278(4):H1241–H1247
Weisbrod RM, Shiang T, Al Sayah L et al (2013) Arterial stiffening precedes systolic hyper-
tension in diet-induced obesity. Hypertension 62(6):1105–1110
Arribas SM, Briones AM, Bellingham C et al (2008) Heightened aberrant deposition of hard-
wearing elastin in conduit arteries of prehypertensive SHR is associated with increased stiff-
ness and inward remodeling. Am J Physiol Heart Circ Physiol 295(6):H2299–H2307
González JM, Briones AM, Somoza B et al (2006) Postnatal alterations in elastic fiber
organization precede resistance artery narrowing in SHR. Am J Physiol Heart Circ Physiol
291(2):H804–H812
Mutchler SM, Straub AC (2015) Compartmentalized nitric oxide signaling in the resistance
vasculature. Nitric Oxide 49:8–15
Takakura K, Beckman JS, MacMillan-Crow LA et al (1999) Rapid and irreversible inac-
tivation of protein tyrosine phosphatases PTP1B, CD45, and LAR by peroxynitrite. Arch
Biochem Biophys 369(2):197–207
Tanner JJ, Parsons ZD, Cummings AH et al (2011) Redox regulation of protein tyrosine
phosphatases: structural and chemical aspects. Antioxid Redox Signal 15(1):77–97
Clément-Chomienne O, Walsh MP, Cole WC (1996) Angiotensin II activation of protein
kinase C decreases delayed rectifier K+ current in rabbit vascular myocytes. J Physiol 495(Pt
3):689–700
Hayabuchi Y, Standen NB, Davies NW (2001) Angiotensin II inhibits and alters kinetics of
voltage-gated K(+) channels of rat arterial smooth muscle. Am J Physiol Heart Circ Physiol
281(6):H2480–H2489
Kubo M, Quayle JM, Standen NB (1997) Angiotensin II inhibition of ATP-sensitive K+ cur-
rents in rat arterial smooth muscle cells through protein kinase C. J Physiol 503(Pt 3):489–496
Spinetti G, Wang M, Monticone R et al (2004) Rat aortic MCP-1 and its receptor CCR2
increase with age and alter vascular smooth muscle cell function. Arterioscler Thromb Vasc
Biol 24(8):1397–1402
Wang G, Anrather J, Glass MJ et al (2006) Nox2, Ca2+, and protein kinase C play a role
in angiotensin II-induced free radical production in nucleus tractus solitarius. Hypertension
48(3):482–489
Wang M, Zhang J, Spinetti G et al (2005) Angiotensin II activates matrix metalloproteinase
type II and mimics age-associated carotid arterial remodeling in young rats. Am J Pathol
167(5):1429–1442
