Biology Today - May 2018

(Rick Simeone) #1

Fibrillation
Fibrillation is a condition in which the heart muscle contracts
very rapidly but in an uncoordinated fashion. There are atrial and
ventricular fibrillation. Ventricular fibrillation is life threatening
unless it can be stopped by defibrillation. A machine called a
defibrillator is used to do this.


Heart failure (Congestive heart failure)
It is a collection of signs and symptoms that occur when the heart
fails to pump an adequate cardiac output. Heart failure is not the
same as cardiac arrest (when the heart stops beating) or heart attack
(when the heart muscle is suddenly damaged by inadequate blood
supply).


Rheumatic Heart Disease (RHD)
The patient may have an acute rheumatic fever, joint pains and
infection of throat. Rheumatic fever may cause permanent damage
of one or more valves (mitral or aortic semilunar valves), pericarditis
and myocarditis. Its causative factor is Streptococcus bacteria.


Ebstein’s disease
It is a congenital downward displacement of the tricuspid valve
into the right ventricle.


Angina pectoris
Sclerosis of the coronary arteries can cause pain in the chest.
This anginal pain usually starts in the centre of the chest and
spreads down the left arm. The chest pain may be associated with
restlessness, fear or anxiety, a pale skin, profuse sweating and
vomiting (all because of increased adrenergic discharge). The pain
lasts for only a few moments.


Arteriosclerosis
It is the hardening and thickening of the arteries due to the
deposition of calcium salts and cholesterol. Such artery loses
the property of distension and its walls may rupture, resulting in the
formation of clot or thrombosis in the coronary artery leading to
heart attack and even death.


Hypertension
It is the most common disease affecting the heart and blood vessels.
A blood pressure of 120/80 mmHg is considered normal. But the
increase in blood pressure beyond 140 mmHg (systolic) and 90
mmHg (diastolic) is called high blood pressure (hypertension). A
diet full of oily food, is known to increase cholesterol level, causing
thickening of the arteries which results in high blood pressure.
Tobacco smoking increases the heart rate, contracts blood vessels
and raises blood pressure. High blood pressure can harm heart,
brain, kidneys and eyes.


Cardiac arrest
It is the complete stoppage of the heartbeat (sudden and complete
loss of cardiac function).


Ischaemia
It is inadequate flow of blood to a part of the heart caused by
obstruction to its blood supply.

Congenital heart diseases
Defects or diseases of the heart from the birth are known as congenital
heart diseases and are due to some error in the development of the
heart. It is possible that some of these defects may be due to an
infectious disease like rubella (German measles) in the mother or
administration of some harmful drugs during first three months of
pregnancy. A small number of cases of congenital heart diseases are
associated with chromosomal abnormalities.

Heart attack
Heart attack, also called myocardial infarction (MI), refers to a
sudden event in which a portion of the heart muscle stops working
because it no longer receives blood, usually due to a blockage in the
coronary artery. Generally, a heart attack occurs when plaque (fat,
cholesterol and calcium) builds up and then ruptures in the coronary
artery, creating a place where a blood clot can form (thrombus).
Signs of heart attack : Chest pain; pain or discomfort in the
upper body (arms, back, neck, jaws or stomach); shortness of breath
(usually occurs at the same time as chest pain); cold sweat; nausea
or vomiting and light headedness.
Controllable risk factors : High cholesterol; cigarette smoking;
excess weight; sedentary lifestyle; stress; high blood pressure;
diabetes and certain drugs, such as oral contraceptives for women
who smoke.

Atherosclerosis /Coronary Artery Disease (CAD)
It is the deposition of lipids (cholesterol) on the wall lining the lumen
of arteries called atheromatous or atherosclerotic plaque. These
plaques may completely block the artery. Such plaques, if formed in
the coronary artery, reduce the blood supply to the heart and may
result in heart attack or stroke.

Heart block
It is a condition in which the sinus node is normal but the impulses
are interrupted at any point along the conducting system of the heart.
Thus, impulses do not follow the normal conduction pathway. Two
common types of heart block are :
AV block : It occurs at the atrioventricular node. The impulses from
the SA node do not reach the AV node.
Bundle branch block : It involves one of the branches of the bundle
of His.

Coronary thrombosis
A clot may form in the lumen of a coronary artery, it is called
coronary thrombosis. Therefore, a large portion of the heart
muscle is deprived of blood and the patient develops a ‘heart
attack’. Anticoagulant drugs like TPA (tissue plasminogen factor)
and streptokinase helps to prevent the formation and extension of
blood clots if given within 4 hours of attack.

DISORDERS OF CIRCULATORY SYSTEM

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