Infectious Agents Associated Cancers Epidemiology and Molecular Biology

(Nora) #1

121



  1. Cheng F et  al (2015) Screening of the human Kinome identifies MSK1/2-CREB1 as an
    essential pathway mediating Kaposi’s sarcoma-associated herpesvirus lytic replication dur-
    ing primary infection. J Virol 89(18):9262–9280

  2. Sadagopan S et  al (2007) Kaposi’s sarcoma-associated herpesvirus induces sustained
    NF-kappaB activation during de novo infection of primary human dermal microvascular
    endothelial cells that is essential for viral gene expression. J Virol 81(8):3949–3968

  3. Zhao Q et al (2015) Kaposi’s sarcoma-associated herpesvirus-encoded replication and tran-
    scription activator impairs innate immunity via ubiquitin-mediated degradation of myeloid
    differentiation factor 88. J Virol 89(1):415–427

  4. Cai Q et al (2010) Molecular biology of Kaposi’s sarcoma-associated herpesvirus and related
    oncogenesis. Adv Virus Res 78:87–142

  5. Kedes DH et al (1997) Identification of the gene encoding the major latency-associated nuclear
    antigen of the Kaposi’s sarcoma-associated herpesvirus. J Clin Invest 100(10):2606–2610

  6. Cai X et  al (2005) Kaposi’s sarcoma-associated herpesvirus expresses an array of viral
    microRNAs in latently infected cells. Proc Natl Acad Sci U S A 102(15):5570–5575

  7. Kellam P et al (1997) Identification of a major latent nuclear antigen, LNA-1, in the human
    herpesvirus 8 genome. J Hum Virol 1(1):19–29

  8. Rainbow L et al (1997) The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi’s
    sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a compo-
    nent of the latency-associated nuclear antigen. J Virol 71(8):5915–5921

  9. Ballestas ME, Chatis PA, Kaye KM (1999) Efficient persistence of extrachromosomal KSHV
    DNA mediated by latency-associated nuclear antigen. Science 284(5414):641–644

  10. Cotter MA 2nd, Robertson ES (1999) The latency-associated nuclear antigen tethers the
    Kaposi’s sarcoma-associated herpesvirus genome to host chromosomes in body cavity-based
    lymphoma cells. Virology 264(2):254–264

  11. Hu J, Garber AC, Renne R (2002) The latency-associated nuclear antigen of Kaposi’s
    sarcoma-associated herpesvirus supports latent DNA replication in dividing cells. J  Virol
    76(22):11677–11687

  12. Lan K et al (2005) Induction of Kaposi’s sarcoma-associated herpesvirus latency-associated
    nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of
    latency. J Virol 79(12):7453–7465

  13. Radkov SA, Kellam P, Boshoff C (2000) The latent nuclear antigen of Kaposi sarcoma-
    associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras
    transforms primary rat cells. Nat Med 6(10):1121–1127

  14. Lim C et al (2000) Latency-associated nuclear antigen of Kaposi’s sarcoma-associated her-
    pesvirus (human herpesvirus-8) binds ATF4/CREB2 and inhibits its transcriptional activation
    activity. J Gen Virol 81(Pt 11):2645–2652

  15. Chang Y et al (1996) Cyclin encoded by KS herpesvirus. Nature 382(6590):410

  16. Li M et  al (1997) Kaposi’s sarcoma-associated herpesvirus encodes a functional cyclin.
    J Virol 71(3):1984–1991

  17. Direkze S, Laman H (2004) Regulation of growth signalling and cell cycle by Kaposi’s
    sarcoma- associated herpesvirus genes. Int J Exp Pathol 85(6):305–319

  18. Sarek G et  al (2010) Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV
    latency. PLoS Pathog 6(3):e1000818

  19. Ojala PM et  al (1999) Kaposi’s sarcoma-associated herpesvirus-encoded v-cyclin triggers
    apoptosis in cells with high levels of cyclin-dependent kinase 6. Cancer Res 59(19):4984–4989

  20. Ojala PM et al (2000) The apoptotic v-cyclin-CDK6 complex phosphorylates and inactivates
    Bcl-2. Nat Cell Biol 2(11):819–825

  21. Liang X et  al (2011) Murine gamma-herpesvirus immortalization of fetal liver-derived B
    cells requires both the viral cyclin D homolog and latency-associated nuclear antigen. PLoS
    Pathog 7(9):e1002220

  22. Ye FC et al (2008) Kaposi’s sarcoma-associated herpesvirus latent gene vFLIP inhibits viral
    lytic replication through NF-kappaB-mediated suppression of the AP-1 pathway: a novel
    mechanism of virus control of latency. J Virol 82(9):4235–4249


7 KSHV Epidemiology and Molecular Biology

Free download pdf