Infectious Agents Associated Cancers Epidemiology and Molecular Biology

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  1. McGivern DR, Lemon SM (2011) Virus-specific mechanisms of carcinogenesis in hepatitis
    C virus associated liver cancer. Oncogene 30:1969–1983

  2. Calabrese F, Pontisso P, Pettenazzo E, Benvegnu L, Vario A, Chemello L, Alberti A, Valente
    M (2000) Liver cell apoptosis in chronic hepatitis C correlates with histological but not bio-
    chemical activity or serum HCV-RNA levels. Hepatology 31:1153–1159

  3. Bantel H, Lugering A, Poremba C, Lugering N, Held J, Domschke W, Schulze-Osthoff K
    (2001) Caspase activation correlates with the degree of inflammatory liver injury in chronic
    hepatitis C virus infection. Hepatology 34:758–767

  4. Thorgeirsson SS, Grisham JW (2002) Molecular pathogenesis of human hepatocellular car-
    cinoma. Nat Genet 31:339–346

  5. Machida K, Cheng KT, Sung VM, Shimodaira S, Lindsay KL, Levine AM, Lai MY, Lai MM
    (2004) Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobu-
    lin and protooncogenes. Proc Natl Acad Sci U S A 101:4262–4267

  6. Machida K, McNamara G, Cheng KT, Huang J, Wang CH, Comai L, Ou JH, Lai MM (2010)
    Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species
    and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes
    and hepatocytes. J Immunol 185:6985–6998

  7. Machida K, Cheng KT, Sung VM, Lee KJ, Levine AM, Lai MM (2004) Hepatitis C virus
    infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby
    enhances DNA damage and mutations of cellular genes. J Virol 78:8835–8843

  8. Machida K, Cheng KT, Lai CK, Jeng KS, Sung VM, Lai MM (2006) Hepatitis C virus trig-
    gers mitochondrial permeability transition with production of reactive oxygen species, lead-
    ing to DNA damage and STAT3 activation. J Virol 80:7199–7207

  9. Lai CK, Jeng KS, Machida K, Cheng YS, Lai MM (2008) Hepatitis C virus NS3/4A pro-
    tein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation.
    Virology 370:295–309

  10. Yi Z, Chen J, Kozlowski M, Yuan Z (2015) Innate detection of hepatitis B and C virus and
    viral inhibition of the response. Cell Microbiol 17:1295–1303

  11. Marukian S, Andrus L, Sheahan TP, Jones CT, Charles ED, Ploss A, Rice CM, Dustin LB
    (2011) Hepatitis C virus induces interferon-lambda and interferon-stimulated genes in pri-
    mary liver cultures. Hepatology 54:1913–1923

  12. Negash AA, Ramos HJ, Crochet N, Lau DT, Doehle B, Papic N, Delker DA, Jo J, Bertoletti
    A, Hagedorn CH, Gale M Jr (2013) IL-1beta production through the NLRP3 inflammasome
    by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease.
    PLoS Pathog 9:e1003330

  13. Nishitsuji H, Funami K, Shimizu Y, Ujino S, Sugiyama K, Seya T, Takaku H, Shimotohno K
    (2013) Hepatitis C virus infection induces inflammatory cytokines and chemokines mediated
    by the cross talk between hepatocytes and stellate cells. J Virol 87:8169–8178

  14. Lin W, Tsai WL, Shao RX, Wu G, Peng LF, Barlow LL, Chung WJ, Zhang L, Zhao H, Jang
    JY, Chung RT (2010) Hepatitis C virus regulates transforming growth factor beta1 produc-
    tion through the generation of reactive oxygen species in a nuclear factor kappaB-dependent
    manner. Gastroenterology 138:2509–2518. 2518 e2501

  15. Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, Fusco DN, Brisac C, Schaefer EA,
    Cai D, Peng LF, Maneekarn N, Lin W, Chung RT (2016) HCV induces transforming growth
    factor beta1 through activation of endoplasmic reticulum stress and the unfolded protein
    response. Sci Rep 6:22487

  16. Jee MH, Hong KY, Park JH, Lee JS, Kim HS, Lee SH, Jang SK (2016) New mechanism of
    hepatic fibrogenesis: hepatitis C virus infection induces transforming growth factor beta1
    production through glucose-regulated protein 94. J Virol 90:3044–3055

  17. Choi SH, Hwang SB (2006) Modulation of the transforming growth factor-beta signal trans-
    duction pathway by hepatitis C virus nonstructural 5A protein. J Biol Chem 281:7468–7478

  18. Panieri E, Santoro MM (2016) ROS homeostasis and metabolism: a dangerous liason in
    cancer cells. Cell Death Dis 7:e2253


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