Chromogranins from Cell Biology to Physiology and Biomedicine

(nextflipdebug5) #1
245

Hakanson R, Ding XQ, Norlen P, Chen D (1995) Circulating pancreastatin is a marker for the
enterochromaffin-like cells of the rat stomach. Gastroenterology 108:1445–1452
Hashimoto T, Kogire M, Lluis F, Gomez G, Tatemoto K, Greeley GH Jr, Thompson JC (1990)
Stimulatory effect of pancreastatin on gastric acid secretion in conscious dogs. Gastroenterology
99:61–65
Hertelendy ZI, Patel DG, Knittel JJ (1996) Pancreastatin inhibits insulin secretion in RINm5F
cells through obstruction of G-protein mediated, calcium-directed exocytosis. Cell Calcium
19:125–132
Herzig KH, Louie DS, Tatemoto K, Chung OY (1992) Pancreastatin inhibits pancreatic enzyme
secretion by presynaptic modulation of acetylcholine release. Am J Phys 262:G113–G117
Huttner WB, Benedum UM (1987) Chromogranin A and pancreastatin. Nature 325:305
Kitayama N, Tateishi K, Funakoshi A, Miyasaka K, Shimazoe T, Kono A, Iwamoto N, Matsuoka Y
(1994) Pancreastatin molecular forms in normal human plasma. Life Sci 54:1571–1578
Kolch W, Heidecker G, Kochs G, Hummel R, Vahidi H, Mischak H, Finkenzeller G, Marme D,
Rapp UR (1993) Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature
364:249–252
Konecki DS, Benedum UM, Gerdes HH, Huttner WB (1987) The primary structure of human
chromogranin A and pancreastatin. J Biol Chem 262:17026–17030
Leduc R, Hendy GN, Seidah NG, Chretien M, Lazure C (1990) Fragmentation of bovine chromo-
granin A by plasma kallikrein. Life Sci 46:1427–1433
Lewis JJ, Zdon MJ, Adrian TE, Modlin IM (1988) Pancreastatin: a novel peptide inhibitor of pari-
etal cell secretion. Surgery 104:1031–1036
Lindstrom E, Bjorkquist M, Boketoft A, Chen D, Zhao CM, Kimura K, Hakanson R (1997)
Release of histamine and pancreastatin from isolated rat stomach ECL cells. Inflamm Res
46(Suppl 1):S109–S110
Metz-Boutigue MH, Garcia-Sablone P, Hogue-Angeletti R, Aunis D (1993) Intracellular and
extracellular processing of chromogranin A. Determination of cleavage sites. Eur J Biochem
217:247–257
Misra UK, Pizzo SV (2010) Modulation of the unfolded protein response in prostate cancer cells
by antibody-directed against the carboxyl-terminal domain of GRP78. Apoptosis 15:173–182
Misra UK, Deedwania R, Pizzo SV (2006) Activation and cross-talk between Akt, NF-kappaB,
and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of
cell surface-associated GRP78. J Biol Chem 281:13694–13707
Miyasaka K, Funakoshi A, Nakamura R, Kitani K, Shimizu F, Tatemoto K (1989) Effects of por-
cine pancreastatin on postprandial pancreatic exocrine secretion and endocrine functions in the
conscious rat. Digestion 43:204–211
O’Connor DT, Cadman PE, Smiley C, Salem RM, Rao F, Smith J, Funk SD, Mahata SK, Mahata
M, Wen G, Taupenot L, Gonzalez-Yanes C, Harper KL, Henry RR, Sanchez-Margalet V
(2005) Pancreastatin: multiple actions on human intermediary metabolism in  vivo, variation
in disease, and naturally occurring functional genetic polymorphism. J Clin Endocrinol Metab
90:5414–5425
Ohneda A, Koizumi F, Ohneda M (1989) Effect of porcine pancreastatin on endocrine function of
canine pancreas. Tohoku J Exp Med 159:291–298
Peiro E, Miralles P, Silvestre RA, Villanueva ML, Marco J (1989) Pancreastatin inhibits insulin
secretion as induced by glucagon, vasoactive intestinal peptide, gastric inhibitory peptide, and
8-cholecystokinin in the perfused rat pancreas. Metabolism 38:679–682
Sanchez V, Calvo JR, Goberna R (1990) Glycogenolytic effect of pancreastatin in the rat. Biosci
Rep 10:87–91
Sanchez V, Lucas M, Calvo JR, Goberna R (1992) Glycogenolytic effect of pancreastatin in iso-
lated rat hepatocytes is mediated by a cyclic-AMP-independent Ca(2+)-dependent mechanism.
Biochem J 284(Pt 3):659–662
Sanchez-Margalet V (1999) Modulation of insulin receptor signalling by pancreastatin in HTC
hepatoma cells. Diabetologia 42:317–325


Action and Mechanisms of Action of the Chromogranin A Derived Peptide Pancreastatin

Free download pdf