431599_Print.indd

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Fig. 4.16 Multiplexed electrical recording from nanoES innervated


  - 3.2.2 3D Macroporous Chemical Sensors Network...........
- 3.2.3 3D Macroporous Strain Sensors Network.............


  • 3.3 Results and Discussion................................

    • 3.3.1 Imaging Nanowire Device in 3D Structure............

    • 3.3.2 Mapping Chemical Diffusion in Gel.................

    • 3.3.3 Mapping Strain Distribution in Elastomer.............



  • 3.4 Conclusion.........................................

  • Bibliography

  • Innervated Synthetic Tissue...............................

  • 4.1 Introduction........................................

  • 4.2 Experimental

    • 4.2.1 NanoES/Tissue Scaffold..........................

    • 4.2.2 Scaffold Mechanical Properties.....................

    • 4.2.3 Cell Culture

    • 4.2.4 Staining

    • 4.2.5 Characterization................................

    • 4.2.6 Electrical Measurement..........................



  • 4.3 Results and Discussion................................

    • 4.3.1 NanoES Characterization.........................

    • 4.3.2 Mechanics-Driven 3D Self-organization

    • 4.3.3 NanoES/Tissue Scaffold Hybrids...................

    • 4.3.4 Characterization of NanoES/Tissue Interface...........

      • Stimulations 4.3.5 Monitoring of Cell Activity Change to External





  • 4.4 Conclusion.........................................

  • Bibliography

  • 5 Syringe Injectable Electronics..............................

    • 5.1 Introduction........................................

    • 5.2 Experimental

      • 5.2.1 Freestanding Mesh Electronics Fabrication............

      • 5.2.2 Mesh Structure Design...........................

      • 5.2.3 Injection of Mesh Electronics......................

      • 5.2.4 Injection of Mesh Electronics into Behaving Animals....

      • 5.2.5 Mechanical Analysis............................

      • 5.2.6 Electrical Measurement..........................

      • 5.2.7 Characterization................................

      • 5.2.8 Chronic Damage Analysis........................



    • 5.3 Results and Discussion................................

      • 5.3.1 Syringe-Injectable Electronics......................

      • 5.3.2 Parameters for Syringe Injectable Electronics

      • 5.3.3 Syringe-Injectable Electronics for Soft Matters.........





  • Fig. 4.12 Hybrid macroporous nanoelectronic scaffolds...............

  • Fig. 4.13 NanoES innervated synthetic neural tissue.................

  • Fig. 4.14 NanoES innervated synthetic cardiac patch.................

  • Fig. 4.15 Biocompatibility of nanoES.............................

    • synthetic cardiac patch

    • nanoES/neural constructs............................... Fig. 4.17 Multiplexed 3D recording from hybrid self-organized



  • Fig. 4.18 Mesh nanoES innervated synthetic vascular construct.........

  • Fig. 4.19 Synthetic vascular construct enabled pH sensing.............

  • Fig. 5.1 Optical images of electronics structure....................

  • Fig. 5.2 Schematics of mesh design.............................

  • Fig. 5.3 Loading in needle....................................

  • Fig. 5.4 Mechanics of mesh during rolling........................

  • Fig. 5.5 Bonding process.....................................

  • Fig. 5.6 Syringe-injectable electronics...........................

  • Fig. 5.7 Stepwise injection....................................

  • Fig. 5.8 Control of injection process.............................

  • Fig. 5.9 Yield of injection....................................

  • Fig. 5.10 Parameters for injection................................

  • Fig. 5.11 Mechanical analysis for injection process..................

  • Fig. 5.12 Control experiments of thinfilm electronics in needle.........

  • Fig. 5.13 Injectable electronics for soft mater.......................

  • Fig. 5.14 Inject electronics for tissue engineering....................

  • Fig. 5.15 Injectable electronics for brain implants...................

    • neural tissue Fig. 5.16 Interface between electronics and in vivo regenerative



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