Multiphase Bioreactor Design

Medium-Phase Mass Balances

substrate

product

Organic-Solvent-Phase Mass Balances

Within this model two different kinds of parameters can be discerned:

1. parameters that can be manipulated easily by the designer; i.e. operating variables like
   the fluxes of the medium and organic solvent, and hence the hold-up of the different
   phases, initial concentration of substrate and product in the different phases, and
   reactor geometry.


2. parameters that are difficult to manipulate; e.g. the physical parameters like density
   and viscosity of the pure liquids, the mass transfer coefficients, and the diffusion
   coefficients of the compounds.

Multiphase bioreactor design 366