Fig. 4Linear response observed in cellular dynamics. (a) Glycolysis, adapted from [9], (b) Epidermal growth
factor (EGF) signaling, adapted from [10], (c) Toll-like receptor (TLR) 3 signaling, adapted from [11] and (d) TLR
4 signaling, adapted from [12]. All species’ dynamics follow gradual increase and decrease that can be
successfully modeled using mass-action or M-M kinetics
180 Kumar Selvarajoo