Figure 1.3Global rates of amino acid replacement for GPDH, G6PD, PGD, SOD,TPI, and XDH. The time unit (abscissa) is 100 million years.The rateson the right are for replacements×^10−^10per site per year. These rates correspond to comparisons betweenDrosophilasubgenera, mammal orders, or fungi(rows 3, 5, and 7 inTable 1.3). The comparisons betweenDrosophilasubgenera and mammal orders correspond to roughly contemporary time lapses (60Ma and 70 Ma, respectively). Other points in the figure are for other comparisons, such as between kingdoms (1100 Ma) or animalphyla (600 Ma; see alsoTable 1.3). For SOD the rate of 5 on the right isfor comparisons between species within themelanogasterandobscuragroups (see alsoFigure 1.2).MOLECULAR CLOCKS: WHENCE AND WHITHER? 17