Endophytes Crop Productivity and Protection Volume 2 (Sustainable Development and Biodiversity)

Table 10.2 Plant/plant extracts with antihypercholesterolemic activity

Name of plant Extract/plant

part

Model/method Results References

Alchornea

cordifolia

Leaves

n-butanolic

fraction

Streptozotocin-induced

diabetic wistar rats

Significant decrease in

total cholesterol

Mohammed

et al. ( 2012 )

Aloe vera Processed

Aloe veragel

Non-insulin dependent

diabetes mellitus mouse

(feeding mouse with a

high fat diet)

Hypoglycemic and

hypolipidemic activity

Kwanghee

et al. ( 2009 )

Cajanus cajan Methanolic

leaf extract

Alloxan-induced

hyperlipidemia in

diabetic rabbits

Significant decrease in

LDL/HDL ratio

Akinloye

and Solanke

( 2011 )

Curcuma longa Rhizomes

methanol

extract

Alloxan-induced

hyperlipidemia in

diabetic rabbits

Decrease in plasma

triglyceride

Nwozo et al.

( 2009 )

Eclipta

prostrata

Leaves

aqueous

extract

Atherogenic diet

induced hyperlipidemic

rats

Significant decrease on

total cholesterol and

triglycerides

Dhandapani

( 2007 )

Emila

praetermissa

Leaves

aqueous

extract

Wistar rats Hypolipidemic activity Nwodo et al.

( 2014 )

Eugenia

jambolana

Composite

extract of

seeds

Streptozotocin-induced

diabetic male albino rat

Serum lipid profile came

significantly close to

normal level in a dose

dependent manner

Mallick

et al. ( 2006 )

Moringa

oleifera

Leaves

petroleum

ether extract

Fat diet induced obesity

in rats

Antiobesity and

hypolipidemic

Bais et al.

( 2014 )

Pithecellobium

dulce

Leaves

aqueous

extract

Triton Wr-1339

induced hyperlipidemic

rats

Significant decrease in the

levels of serum

cholesterol,

phospholipids,

triglyceride, LDL, VLDL

and significant increase in

the level of serum HDL

Sundarrajan

et al. ( 2010 )

Stachytarphela

augustifolia

Plant

methanolic

extract

Streptozotocin-induced

diabetic wistar rats

Significant decrease in

total cholesterol, low

density lipoprotein and

lipid peroxides as

function of treatment

Garba et al.

( 2013 )

Tephrosia

purpurea

Leaves

ethanolic

extract

Streptozotocin-induced

diabetic rats

600 mg/kg body weight

normalized the lipids and

lipoproteins profile

Pavana et al.

( 2007 )

Urtica dioica Leaves

ethanolic and

aqueous

extract

Alloxan-induced

diabetic or

hyperlipidemic rats

Rats treated with

ethanolic and aqueous

extract showed

significantly reduction in

levels of triglyceride and

cholesterol

Mahjoub

et al. ( 2012 )

10 Endophytes: Potential Source of Therapeutically... 219