Table 10.3List of plant/plant extracts with antidiabetic potentialName of plantExtract/plant partModel/methodResultsReferencesAcalypha indicaAerial partchloroform andethanolic extractIn vitro alpha amylaseinhibition assayShowed IC50value 173.53μ
g/ml for chloroform extract and180.80μ
g/ml for ethanolic extractDineshkumaret al. (2010)AnnonamuricataPlant aqueousextractStreptozotocin-induceddiabetic ratsPlant extract was not effective in normal rats but showed 75%reduction in blood glucose level at 100 mg/kg after 28 daysof treatmentFlorence et al.(^2014)AnthocleistadjalonensisEthanolic rootextractAlloxan-induceddiabetic ratsReduced blood glucose levelOkokon et al.(^2012)AraliataibaiensisPlant totalsaponins extractStreptozotocin-induceddiabetic ratsReduced fasting blood glucose and glycosylated hemoglobin Weng et al.(^2014)AzadirachtaindicaEthanolic leafextractStreptozotocin-induceddiabetic ratsImproved pancreatic lesion in diabetic ratsAkinola et al.(^2010)BerberisaristataBark methanolicextractInhibition of DPP4enzymeShowed IC50value 14.4μg/mlChakrabarti et al.(^2011)Blighia sapidaRoot aqueousextractNormoglycaemic ratsDecreased blood glucose levelSaidu et al.(^2012)Cola acuminataStem methanolicextractAlloxan-induceddiabetic ratsDecreased blood glucose levelAdediwura et al.(^2011)Cucurbita pepoSeed mixturepowderAlloxan-induceddiabetic ratsIncrease in activity of aspartate aminotransferases andalanine aminotransferases as a function of treatmentMakni et al.(^2011)DanielliaoliveriAqueous leafextractAlloxan-induceddiabetic ratsBlood glucose level decreased in both normal and diabeticratsManosroi et al.(^2011)GymnemasylvestreCallus methanolicextractAlloxan-induceddiabetic ratsSignifi
cant increase and regeneration of pancreaticb
-cellsAhmed et al.(^2010)HunteriaumbellateAlkaloid richfractionAlloxan-induceddiabetic ratsDecreased post absorptive glucose concentrationAdewale et al.(^2013) (continued)10 Endophytes: Potential Source of Therapeutically... 223