51
Kissa K, Herbomel P (2010) Blood stem cells emerge from aortic endothelium by a novel type of
cell transition. Nature 464:112–115
Kissa K, Murayama E, Zapata A, Cortes A, Perret E, Machu C, Herbomel P (2008) Live imaging
of emerging hematopoietic stem cells and early thymus colonization. Blood 111:1147–1156
Kobayashi Y (2008) The role of chemokines in neutrophil biology. Front Biosci 13:2400–2407
Kobayashi I, Kobayashi-Sun J, Kim AD, Pouget C, Fujita N, Suda T, Traver D (2014) Jam1a-
Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling. Nature
512:319–323
Kobayashi H, Kobayashi CI, Nakamura-Ishizu A, Karigane D, Haeno H, Yamamoto KN, Sato T,
Ohteki T, Hayakawa Y, Barber GN, Kurokawa M, Suda T, Takubo K (2015) Bacterial c-di-GMP
affects hematopoietic stem/progenitors and their niches through STING. Cell Rep 11:71–84
Kunisaki Y, Bruns I, Scheiermann C, Ahmed J, Pinho S, Zhang D, Mizoguchi T, Wei Q, Lucas D,
Ito K, Mar JC, Bergman A, Frenette PS (2013) Arteriolar niches maintain haematopoietic stem
cell quiescence. Nature 502:637–643
Kwan W, Cortes M, Frost I, Esain V, Theodore LN, Liu SY, Budrow N, Goessling W, North
TE (2016) The central Nervous system regulates embryonic HSPC production via stress-
Responsive glucocorticoid receptor signaling. Cell Stem Cell 19:370–382
Kyba M, Daley GQ (2003) Hematopoiesis from embryonic stem cells: lessons from and for ontog-
eny. Exp Hematol 31:994–1006
Lauring B, Sakai H, Kreibich G, Wiedmann M (1995) Nascent polypeptide-associated complex
protein prevents mistargeting of nascent chains to the endoplasmic reticulum. Proc Natl Acad
Sci U S A 92:5411–5415
Lee JS, Yu Q, Shin JT, Sebzda E, Bertozzi C, Chen M, Mericko P, Stadtfeld M, Zhou D, Cheng
L, Graf T, MacRae CA, Lepore JJ, Lo CW, Kahn ML (2006) Klf2 is an essential regulator of
vascular hemodynamic forces in vivo. Dev Cell 11:845–857
Lee Y, Manegold JE, Kim AD, Pouget C, Stachura DL, Clements WK, Traver D (2014) FGF sig-
nalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling.
Nat Commun 5:5583
Li Y, Esain V, Teng L, Xu J, Kwan W, Frost IM, Yzaguirre AD, Cai X, Cortes M, Maijenburg
MW, Tober J, Dzierzak E, Orkin SH, Tan K, North TE, Speck NA (2014) Inflammatory sig-
naling regulates embryonic hematopoietic stem and progenitor cell production. Genes Dev
28:2597–2612
Lim SE, Esain V, Kwan W, Theodore LN, Cortes M, Frost IM, Liu SY, North TE (2017) HIF1
alpha-induced PDGFRbeta signaling promotes developmental HSC production via IL-6 activa-
tion. Exp Hematol 46:83–95.e6
Lin Z, Kumar A, SenBanerjee S, Staniszewski K, Parmar K, Vaughan DE, Gimbrone MA Jr,
Balasubramanian V, Garcia-Cardena G, Jain MK (2005) Kruppel-like factor 2 (KLF2) regu-
lates endothelial thrombotic function. Circ Res 96:e48–e57
Massague J, Gomis RR (2006) The logic of TGFbeta signaling. FEBS Lett 580:2811–2820
Medvinsky A, Dzierzak E (1996) Definitive hematopoiesis is autonomously initiated by the AGM
region. Cell 86:897–906
Mendez-Ferrer S, Lucas D, Battista M, Frenette PS (2008) Haematopoietic stem cell release is
regulated by circadian oscillations. Nature 452:442–447
Monteiro R, Pinheiro P, Joseph N, Peterkin T, Koth J, Repapi E, Bonkhofer F, Kirmizitas A, Patient
R (2016) Transforming growth factor beta drives hemogenic endothelium programming and
the transition to hematopoietic stem cells. Dev Cell 38:358–370
Murayama E, Kissa K, Zapata A, Mordelet E, Briolat V, Lin HF, Handin RI, Herbomel P (2006)
Tracing hematopoietic precursor migration to successive hematopoietic organs during zebraf-
ish development. Immunity 25:963–975
Murayama E, Sarris M, Redd M, Le Guyader D, Vivier C, Horsley W, Trede N, Herbomel P (2015)
NACA deficiency reveals the crucial role of somite-derived stromal cells in haematopoietic
niche formation. Nat Commun 6:8375
4 Developmental HSC Microenvironments: Lessons from Zebrafish