52
Nguyen PD, Hollway GE, Sonntag C, Miles LB, Hall TE, Berger S, Fernandez KJ, Gurevich DB,
Cole NJ, Alaei S, Ramialison M, Sutherland RL, Polo JM, Lieschke GJ, Currie PD (2014)
Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1.
Nature 512:314–318
North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman
TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI (2007) Prostaglandin E2
regulates vertebrate haematopoietic stem cell homeostasis. Nature 447:1007–1011
North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang
P, Dzierzak E, Zon LI (2009) Hematopoietic stem cell development is dependent on blood flow.
Cell 137:736–748
Orkin SH, Zon LI (2008) Hematopoiesis: an evolving paradigm for stem cell biology. Cell
132:631–644
Parmar KM, Larman HB, Dai G, Zhang Y, Wang ET, Moorthy SN, Kratz JR, Lin Z, Jain MK,
Gimbrone MA Jr, Garcia-Cardena G (2006) Integration of flow-dependent endothelial pheno-
types by Kruppel-like factor 2. J Clin Invest 116:49–58
Pierce H, Zhang D, Magnon C, Lucas D, Christin JR, Huggins M, Schwartz GJ, Frenette PS
(2017) Cholinergic signals from the CNS regulate G-CSF-mediated HSC mobilization from
bone marrow via a glucocorticoid signaling relay. Cell Stem Cell 20:648–658.e4
Pillay LM, Mackowetzky KJ, Widen SA, Waskiewicz AJ (2016) Somite-derived retinoic acid reg-
ulates Zebrafish hematopoietic stem cell formation. PLoS One 11:e0166040
Pombo-de-Oliveira MS, Koifman S, Brazilian L, Collaborative Study Group of Infant Acute
(2006) Infant acute leukemia and maternal exposures during pregnancy. Cancer Epidemiol
Biomark Prev 15:2336–2341
Pouget C, Peterkin T, Simoes FC, Lee Y, Traver D, Patient R (2014) FGF signalling restricts hae-
matopoietic stem cell specification via modulation of the BMP pathway. Nat Commun 5:5588
Robertson AL, Avagyan S, Gansner JM, Zon LI (2016) Understanding the regulation of vertebrate
hematopoiesis and blood disorders—big lessons from a small fish. FEBS Lett 590:4016–4033
Sawamiphak S, Kontarakis Z, Stainier DY (2014) Interferon gamma signaling positively regulates
hematopoietic stem cell emergence. Dev Cell 31:640–653
Simard M, Drolet R, Blomquist CH, Tremblay Y (2011) Human type 2 17beta-hydroxysteroid
dehydrogenase in umbilical vein and artery endothelial cells: differential inactivation of sex
steroids according to the vessel type. Endocrine 40:203–211
Sousa JB, Diniz C (2017) The adenosinergic system as a therapeutic target in the vasculature: new
ligands and challenges. Molecules 22
Stachura DL, Svoboda O, Campbell CA, Espin-Palazon R, Lau RP, Zon LI, Bartunek P, Traver D
(2013) The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines
and their roles in hematopoietic development and maintenance. Blood 122:3918–3928
Takizawa H, Regoes RR, Boddupalli CS, Bonhoeffer S, Manz MG (2011) Dynamic variation in
cycling of hematopoietic stem cells in steady state and inflammation. J Exp Med 208:273–284
Takizawa H, Boettcher S, Manz MG (2012) Demand-adapted regulation of early hematopoiesis in
infection and inflammation. Blood 119:2991–3002
Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI
(2015) Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche.
Cell 160:241–252
Travnickova J, Tran Chau V, Julien E, Mateos-Langerak J, Gonzalez C, Lelievre E, Lutfalla G,
Tavian M, Kissa K (2015) Primitive macrophages control HSPC mobilization and definitive
haematopoiesis. Nat Commun 6:6227
Tulchinsky D, Hobel CJ, Yeager E, Marshall JR (1972) Plasma estrone, estradiol, estriol, proges-
terone, and 17-hydroxyprogesterone in human pregnancy I Normal pregnancy. Am J Obstet
Gynecol 112:1095–1100
Walmsley M, Ciau-Uitz A, Patient R (2002) Adult and embryonic blood and endothelium derive
from distinct precursor populations which are differentially programmed by BMP in Xenopus.
Development 129:5683–5695
S. Nik et al.