Imaging in Stem Cell Transplant and Cell-based Therapy

(Nancy Kaufman) #1

© Springer International Publishing AG 2017 37
T. Pandey (ed.), Imaging in Stem Cell Transplant and Cell-based Therapy,
Stem Cell Biology and Regenerative Medicine, DOI 10.1007/978-3-319-51833-6_3


Chapter 3

Radiologic Procedures Used in Pediatric Stem


Cell Transplantation


Mohammad Atiq, Terry Harville, Nishi Shah, Paulette Mehta,
Tarun Pandey, and Yogesh S. Jethava


3.1 Introduction


Radiologic procedures form one of the cornerstones of diagnosis in hematological
malignancies. Various radiological procedures are essential for the diagnosis,
assessment of the therapeutic response, to identify disease relapse, and to evaluate
for complications pre- and post-transplantation. The significance of radiology and
radiological procedures in stem cell transplantation is expected to grow. In this
chapter, we discuss the radiologic procedures and review the key imaging modali-
ties and implications related to pediatric hematopoietic stem cell transplant (HSCT).
We will also discuss the role of radionuclide Imaging for patients undergoing hema-
topoietic stem cell transplantation with a brief review of use of radio-labeled MIBG
imaging in children with Neuroblastoma.


M. Atiq, M.D.
Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock,
AR, USA


T. Harville, Ph.D.
Department of Pathology, University of Arkansas, Little Rock, AR, USA


N. Shah, M.D.
Department of Internal Medicine, University of Arkansas, Little Rock, AR, USA


Paulette Mehta, M.D., M.P.H. • Y.S. Jethava, M.D.(*)
Department of Internal Medicine (Hem-Onc), University of Arkansas, Little Rock, AR, USA
e-mail: [email protected]


T. Pandey, M.D., F.R.C.R.
Department of Radiology, University of Arkansas, 4301 West Markham Street, Little Rock,
AR 72205, USA

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