© Springer International Publishing AG 2017 87
T. Pandey (ed.), Imaging in Stem Cell Transplant and Cell-based Therapy,
Stem Cell Biology and Regenerative Medicine, DOI 10.1007/978-3-319-51833-6_6
Chapter 6
Simultaneous MRI and 18F-FDG-PET
Imaging in Multiple Myeloma: A Model
for Evaluation of the Disease
and Therapeutic Changes in SCID-hu Mice
Tarun K. Garg and Tarun Pandey
Abbreviations
FDG-PET 18 F–Fluorodeoxyglucose-positron emission tomography
ASCT Autologous stem cell transplantation
BLI Bioluminescence imaging
CAR-T Chimeric antigen receptor-T
CT Computed tomography
DCE-MRI Dynamic contrast-enhanced MRI
ELISA Enzyme-linked immunosorbent assay
Exp-NK Expanded natural killer
hIg Human immunoglobulins
iNKT Invariant natural killer T cells
MRI Magnetic resonance imaging
MGUS Monoclonal gammopathy of undetermined significance
MM Multiple myeloma
NOD/SCID/IL2Rγnull-Hu Non-obese diabetic-SCID-IL2 receptor gamma
null-human
PET Positron emission tomography
SCID Severe-combined immunodeficiency
T.K. Garg (*)
Myeloma Institute, University of Arkansas for Medical Sciences (UAMS), 4301 West
Markham, Little Rock, AR 72205, USA
e-mail: [email protected]
T. Pandey
Department of Radiology, University of Arkansas for Medical Sciences, 4301 West Markham
Street, Little Rock, AR 72205, USA
e-mail: [email protected]