Biomimetic Structured Porogen Freeform Fabrication System for Tissue Engineering
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(A) (B) (C)
Fig. 10. 3-D reconstruction from μCT data (A) pure PCL scaffold (B) 90/10 scaffold (C) 80/20
scaffold.
ANOVA test for independent variables was used to check for differences between results
obtained for different materials. Pure PCL cylinders had average UCS of 12.4MPa and CM
of 275MPa. Cylinders with 90% PCL and 10%CaP had average UCS of 19.5MPa and CM of
341MPa, where as cylinders with 80% PCL and 20%CaP had average UCS of 24.8MPa and
CM of 425MPa. Increasing stiffness of the material, under compression loading, with the
increase of percentage of CaP has been found by the statistical analysis. The UCS increased
57.3% from pure PCL to 90/10 PCL-CaP composite material and 100% from PCL to 80/20
PCL-CaP composite material while the CM increased 24% from pure PCL to 90/10 PCL-CaP
composite material and 54.5% from PCL to 80/20 PCL-CaP composite material.
Fig. 11. Compressive mechanical properties of PCL-CaP composite cylinders.
A: Comparison of the compressive modulus of 100% PCL, 90:10 and 80:20 PCL-CaP
cylinders; B: Comparison of the ultimate compressive strength with different concentrations
of CaP. Statistical analysis indicates that the material properties are significantly different (p
< 0.002) for different concentrations of CaP.
A B