Revival: Biological Effects of Low Level Exposures to Chemical and Radiation (1992)

(Barry) #1
Index

Accelerated maturation time, 42
Acclimation, 42
ACDQ. See 6-Amino-7-chloro-5,8-
dioxoquinoline
Acetamido iminoquinone, 60
Acetaminophen metabolites, 60. See
also specific types
Adaptation, 113-117, 139-142
Adaptive-physiological view of
carcinogenesis, 115-117
Adaptive repair, 139-140
Adenosine diphosphate-ribose, 45
Adenosine triphosphate, 46, 67, 83
Adenylated nucleotides, 45
ADP. See Adenosine diphosphate
Adversarial-confrontational view of
carcinogenesis, 115
Aflatoxin B, 55
Age-specific mortality rate, 1, 2, 4, 14
Aging, 1, 4
defined, 2, 10
DNA repair and, 53-56
gradualist, uniform view of, 7
as inevitable, 5
wear-and-tear theory of, 2
Alarmones, 45
Alcohols, 41, 45, 47, 63. See also
specific types
Aldehydes, 5
Aliphatic alcohols, 63. See also specific
types
Alkylating agents, 56. See also specific
types
Alkyltransferase, 56
Allometric scaling principles, 10-12
6-Amino-7-chloro-5,8-dioxoquinoline
(ACDQ), 45
Amosite asbestos, 15, 23-24, 26, 27
Anesthetics, 44. See also specific types
Antibiotics, 41. See also specific types
Antigens, 101, 102, 103


Antihypertensive agents, 10. See also
specific types
Antimitosis, 78
Antioxidants, 4, 9. See also specific
types
Anxiety, 6
Apoptosis/interphase cell death, 98
Appetite abatement, 9
Arsenite, 47
Asbestos, 15, 23-24, 26, 27
ATP. See Adenosine triphosphate
Autoimmunity, 106, 109-110
Autoprotection, 62-63, 77
Autoradiography, 72

B-cells, 96, 97, 98, 104, 107
Bioassays, 4
Biochemical studies, 71
Biological disorder, 10
Biomarkers, 42
Bone marrow, 98
Bone marrow-derived cells. See B-cells
Bromotrichloromethane, 62, 63, 64

Cadmium, 47
Cadmium chloride, 45
Calcium, 66, 70, 71, 83
Calcium-dependent endonuclease, 106
Caloric restriction, 4, 8, 9, 14, 19, 28,
33
Cancer, 30, 44, 55, 59, 114-117. See
also specific types
Carbon tetrachloride, 61-62
autoprotection of, 62-63, 77
bioactivation of, 61, 62, 63, 66, 68,
69, 70, 71, 78, 80
chlordecone and, 61, 64-67, 70, 73,
75
hormesis nonexpression and,
75-76
two-stage toxicity model and, 79,
82, 83, 84

149
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