Revival: Biological Effects of Low Level Exposures to Chemical and Radiation (1992)

INDEX 151

Electromagnetic radiation, 41
Electrophoresis, 106
Emax model (logarithmic-logistic
function), 13
Endocrine system, 5
Endonuclease, 106
Entropy accumulation, 5
Enzymes, 45, 46. See also specific
types
EPF. See Extracellular inducing factor
Epigenetic process, 114
Escherichia coli, 45, 55
Estrous, 55
Ethanol, 41, 45, 47
Ethyl acrylate, 15, 24, 28
External healthy worker effect, 32
Exterogestation, 12
Extracellular inducing factor (EPF),
45
Extrapolation across species, 23

Fats, 6

Fibroblasts, 54

First-order mortality rate constant, 2

First-order repair rate constant, 7

First-order toxicity rate constant, 7

Force of mortality. See Hazard

function

Free radicals, 5, 60, 61, 62, 63, 70

Fruit flies (Drosophila spp.), 4, 43, 44,

47

Gamma radiation, 15, 21, 22, 41
Gender specificity of longevity
hormesis, 17
Generalized Gompertz function. See
Gompertz function
Generalized hyperbolic function
(logarithmic-logistic function), 13
Gene rearrangements, 114
Generic concept of hormesis, 3
Genomic damage, 56
Genomic disease, 114
Glutathione, 60, 62, 66
Glycogen, 68, 71
Glycogenolysis, 71
Gompertz function, 1-33
defined, 2
hypotheses about, 5-14

linear, 6-7, 8, 13, 14, 16, 17, 19, 28

longevity hormesis and. See

Longevity hormesis

reduction in, 8-9

superimposition onto, 8

survivalship function in, 19

Gompertzian. See Gompertz function

Gompertz-Makeham function, 5

Gompertz plots, 19, 24, 25, 26, 27, 28,

29, 30, 31

Gompertz transform. See Gompertz

function

Good animal husbandry, 6

Growth hormesis, 3

GSH. See Glutathione

Halomethane hepatotoxicity

chlordecone and, 61, 64-67, 70, 73,

75

hormesis nonexpression and, 75

two-stage toxicity model and, 79,

82, 83, 84

mechanism of, 61-63

potentiation of, 63-85

cell division and, 73-79

public health and, 64, 84-85

tissue repair and, 67-79

two-stage model and, 79-84

sensitivity to, 76-77

two-stage model of, 79-84

Hanford nuclear weapons site, 30-32

Hazard function, 1, 6, 9

Napierian logarithm of. See

Gompertz function

Healing, 59, 61, 84. See also Repair

Healthy worker effect, 32

Heat, 41, 43-44, 47

Heat shock agents, 47. See also

specific types

Heat shock genes, 46-47

Heat shock proteins, 43-44, 46, 47.

See also specific types

Heat shock response (stress protein

response), 41-48

Heavy metals, 41. See also specific

types

Helper T-cells, 105

Hemoglobin synthesis, 5

Hepatocellular regeneration, 60