276 Ulrich Krohs
Lewontin, R. C. (1978). Adaptation. Scientifi c American, 239: 156–169.
Margulis, L. (1970). Origin of Eukaryotic Cells. New Haven: Yale University Press.
Margulis, L. (1981). Symbiosis in Cell Evolution. San Francisco: W. H. Freeman.
Onami, S., Kyoda, K. M., Morohashi, M., and Kitano, H. (2002). The DBRF method for inferring a gene network
from large-scale steady-state gene expression data. In: Foundations of Systems Biology (Kitano, H., ed.), 59–75.
Cambridge, Mass.: The MIT Press.
Owen, O. E., Kalhan, S. C., and Hanson, R. W. (2002). The key role of anaplerosis and cataplerosis for citric
acid cycle function. Journal of Biological Chemistry, 277: 30409–30412.
Pahl, G., Beitz, W., Feldhusen, J., and Grote, K. H. (2007). Engineering Design: A Systematic Approach, 3rd
ed. London: Springer.
Palsson, B. Ø. (2006). Systems Biology. Cambridge, Mass.: Cambridge University Press.
Papin, J. A., Reed, J. L., and Palsson, B. O. (2004). Hierarchical thinking in network biology: The unbiased
modularization of biochemical networks. Trends in Biochemical Sciences, 29: 641–647.
Raff, R. A. (1996). The Shape of Life: Genes, Development, and the Evolution of Animal Form. Chicago: Uni-
versity of Chicago Press.
Rohwer, J. M., Schuster, S., and Westerhoff, H. V. (1996). How to recognize monofunctional units in a metabolic
system. Journal of Theoretical Biology, 179: 213–228.
Sagan, L. [Margulis, L.] (1967). On the origin of mitosing cells. Journal of Theoretical Biology, 14: 225–274.
Sarnecki, J. (2007). Developmental objections to evolutionary modularity. Biology and Philosophy, 22:
529–546.
Schaffner, K. F. (1998). Genes, behavior, and developmental emergentism: One process, indivisible? Philosophy
of Science, 65: 209–252.
Schank, J. C., and Wimsatt, W. C. (2001). Evolvability, adaptation and modularity. In: Thinking About Evolution,
Vol. 2: Historical, Philosophical, and Political Perspectives (Sing, R. S., Krimbas, C. B., Paul, D. B., and Beatty,
J., eds.), 322–335. New York: Cambridge University Press.
Schlosser, G. (2005). Amphibian variations: The role of modules in mosaic evolution. In: Modularity (Callebaut,
W., and Rasskin-Gutman, D., eds.), 143–179. Cambridge, Mass.: The MIT Press.
Schlosser, G., and Wagner, G. P. (eds.). (2004). Modularity in Development and Evolution. Chicago: University
of Chicago Press.
Simon, H. A. (1969 [1996]). The Sciences of the Artifi cial, 3rd ed. Cambridge, Mass.: The MIT Press.
Sober, E. (1984). The Nature of Selection. Cambridge, Mass.: The MIT Press.
Ulrich, K. T., and Eppinger, S. D. (2003). Product Design and Development, 3rd ed. Boston: McGraw Hill.
Wagner, G. P., and Altenberg, L. (1996). Perspective: Complex adaptations and the evolution of evolvability.
Evolution, 50: 967–976.
Wagner, G. P., Mezey, J., and Calabretta, R. (2005). Natural selection and the origin of modules. In: Modularity
(Callebaut, W., and Rasskin-Gutman, D., eds.), 33–49. Cambridge, Mass.: The MIT Press.
White, K. P. (1999). Systems design. In: Handbook of Systems Engineering and Management (Sage, A. P., Rouse,
W. B., eds.), 455–481. New York: Wiley.