Drug Metabolism in Drug Design and Development Basic Concepts and Practice

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Her C, Raftogianis R. et al. Human phenol sulfotransferase STP2 gene: molecular
cloning, structural characterization, and chromosomal localization. Genomics
1996;33(3):409–420.
Itoh K, Tong KI, Yamamoto M. Molecular mechanism activating Nrf2-Keap1 pathway
in regulation of adaptive response to electrophiles. Free Radic Biol Med
152004;36(10):1208–1213.
Jowsey IR, Thomson AM, Flanagan JU. et al. Mammalian class Sigma glutathione
S-transferases: catalytic properties and tissue-specific expression of human and
rat GSH-dependent prostaglandin D2 synthases. Biochem J 2001;359(Pt 3):507–516.
Kulp KS, Knize MG. et al. Identification of urine metabolites of 2-amino-1-methyl-6-
phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken
meal in humans. Carcinogenesis 2000;21(11):2065–2072.
Liu L, Klaassen CD. Regulation of hepatic sulfotransferases by steroidal chemicals in
rats. Drug Metab Dispos 1996;24(8):854–858.
Maglich JM, Parks DJ. et al. Identification of a novel human constitutive androstane
receptor (CAR) agonist and its use in the identification of CAR target genes. J Biol
Chem 2003;278(19):17277–17283.
Mannervik B, Board PG, Hayes JD, Listowsky I, Pearson WR. Nomenclature for
mammalian soluble glutathione transferases. Methods Enzymol 2005;401:1–8.
Marchetti F, De Santi C. et al. Differential inhibition of human liver and duodenum
sulphotransferase activities by quercetin, a flavonoid present in vegetables, fruit and
wine. Xenobiotica 2001;31(12):841–847.
Matsuno K, Kubota T, Matsukura Y, Ishikawa H, Iga T. Genetic analysis of
glutathione S-transferase A1 and T1 polymorphisms in a Japanese population. Clin
Chem Lab Med 2004;42(5):560–562.
McWalter GK, Higgins LG, McLellan LI. et al. Transcription factor Nrf2 is essential
for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases,
and glutamate cysteine ligase by broccoli seeds and isothiocyanates. J Nutr
2004;134(12 Suppl):3499S–3506S.
Morgenstern R. Microsomal glutathione transferase 1. Methods Enzymol 2005;401:
136–146.
Motohashi H, Yamamoto M. Nrf2-Keap1 defines a physiologically important stress
response mechanism. Trends Mol Med 2004;10(11):549–557.
Mulder GJ, Scholtens E. Phenol sulphotransferase and uridine diphosphate glucur-
onyltransferase from rat liverin vivo and vitro. 2,6-Dichloro-4-nitrophenol as
selective inhibitor of sulphation. Biochem J 1977;165(3):553–559.
Nagar S, Walther S. et al. Sulfotransferase (SULT) 1A1 polymorphic variants^ 1,^ 2,
and^ 3 are associated with altered enzymatic activity, cellular phenotype, and protein
degradation. Mol Pharmacol 2006;69(6):2084–2092.
Nakajima M, Yamato S. et al. Determination of dehydroepiandrosterone sulphate in
biological samples by liquid chromatography/atmospheric pressure chemical
ionization-mass spectrometry using [7,7,16,16-2H4]-dehydroepiandrosterone sul-
phate as an internal standard. Biomed Chromatogr 1998;12(4):211–216.
Ntais C, Polycarpou A, Ioannidis JP. Association of GSTM1, GSTT1, and GSTP1 gene
polymorphisms with the risk of prostate cancer: a meta-analysis. Cancer Epidemiol
Biomarkers Prev 2005;14(1):176–181.


86 CONJUGATIVE METABOLISM OF DRUGS

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