Chien JY, Thummel KE, Slattery JT. Pharmacokinetic consequences of induction of
CYP2E1 by ligand stabilization. Drug Metab Dispos 1997;25:1165–1175.
Crespi CL. Xenobiotic-metabolizing human cells as tools for pharmacological and
toxicological research. Advance in Drug Research. New York: Academic Press; 1995.
p 179–235.
Crespi CL, Penman BW. Use of cDNA-expressed human cytochrome P450 enzymes to
study potential drug–drug interactions. Adv Pharmacol 1997;43:171–188.
de Kanter R, Monshouwer M, Meijer DK, Groothuis GM. Precision-cut organ slices as
a tool to study toxicity and metabolism of xenobiotics with special reference to
nonhepatic tissues. Curr Drug Metab 2002;3:39–59.
Ding X, Staudinger JL. Induction of drug metabolism by forskolin: the role of the
pregnane x receptor and the protein kinase a signal transduction pathway. J
Pharmacol Exp Ther 2005;312:849–856.
DixitSG, TironaRG, KimRB. BeyondCAR and PXR.Curr DrugMetab2005;6:385–397.
Eichelbaum M, Ekbom K, Bertilsson L, Ringberger VA, Rane A. Plasma kinetics of
carbamazepine and its epoxide metabolite in man after single and multiple doses. Eur
J Clin Pharmacol 1975;8:337–341.
Galetin A, Burt H, Gibbons L, Houston JB. Prediction of time-dependent
CYP3A4 drug–drug interactions: impact of enzymedegradation, parallel elimina-
tion pathways, and intestinal inhibition. DrugMetab Dispos 2006;34:166–175.
Gebhardt R, Hengstler JG, Muller D, Glockner R, Buenning P, Laube B, Schmelzer E,
Ullrich M, Utesch D, Hewitt N, Ringel M, Hilz BR, Bader A, Langsch A, Koose T,
Burger HJ, Maas J, Oesch F. New hepatocyte in vitro systems for drug
metabolism: metabolic capacity and recommendations for application in basic
research and drug development, standard operation procedures. Drug Metab Rev
2003;35:145–213.
Gelboin HV, Krausz KW, Gonzalez FJ, Yang TJ. Inhibitory monoclonal antibodies to
human cytochrome P450 enzymes: a new avenue for drug discovery. Trends
Pharmacol Sci 1999;20:432–438.
Glass CK, Rose DW, Rosenfeld MG. Nuclear receptor coactivators. Curr Opin Cell
Biol 1997;9:222–232.
Glass CK, Rosenfeld MG. The coregulator exchange in transcriptional functions of
nuclear receptors. Genes Dev 2000;14:121–141.
Gomez-Lechon MJ, Donato MT, Castell JV, Jover R. Human hepatocytes in primary
culture: the choice to investigate drug metabolism in man. Curr Drug Metab
2004;5:443–462.
Grub S, Bryson H, Goggin T, Ludin E, Jorga K. The interaction of saquinavir (soft
gelatin capsule) with ketoconazole, erythromycin and rifampicin: comparison of the
effect in healthy volunteers and in HIV-infected patients. Eur J Clin Pharmacol
2001;57:115–121.
Hall SD, Wang Z, Huang SM, Hamman MA, Vasavada N, Adigun AQ, Hilligoss JK,
Miller M, Gorski JC. The interaction between St John’s wort and an oral
contraceptive. Clin Pharmacol Ther 2003;74:525–535.
Hallifax D, Rawden HC, Hakooz N, Houston JB. Prediction of metabolic clearance
using cryopreserved human hepatocytes: kinetic characteristics for five benzodiaze-
pines. Drug Metab Dispos 2005;33:1852–1858.
REFERENCES 131