Hazai I, Patfalusi M, Klebovich I, Urmos I. Whole-body autoradiography and
quantitative organ-level distribution study of deramciclane in rats. J Pharm
Pharmacol 1999;51:165–174.
Heath TG, Mooney JP, Broersma R. Narrow-bore liquid chromatography-tandem
mass spectrometry with simultaneous radioactivity monitoring for partially
characterizing the biliary metabolites of an arginine fluoroalkyl ketone analog of
D-MePhe-Pro-Arg, a potent thrombin inhibitor. J Chromatogr B Biomed Sci Appl
1997;688:281–289.
Hyllbrant B, Tyrefors N, Markides KE, Langstrom B. On the use of liquid
chromatography with radio- and ultraviolet absorbance detection coupled to mass
spectrometry for improved sensitivity and selectivity in determination of specific
radioactivity of radiopharmaceuticals. J Pharm Biomed Anal 1999;20:493–501.
Hett KF, Ethell BT, Maggs JL, Davis TM, Batty KT, Burchell B, Binh TQ, Thu le TA,
Hung NC, Pirmohamed M, Park BK, Edwards G. Glucuronidation of dihydroarte-
misininin vivoand by human liver microsomes and expressed UDP-glucuronosyl-
transferases. Drug Metab Dispos 2002;30:1005–1012.
Johnson KA, Plumb R. Investigating the human metabolism of acetaminophen using
UPLC and exact mass oa-TOF MS. J Pharm Biomed Anal 2005;39:805–810.
Kiffe M, Jehle A, Ruembeli R. Combination of high-performance liquid chromato-
graphy and microplate scintillation counting for crop and animal metabolism
studies: a comparison with classical on-line and thin-layer chromatography radio-
activity detection. Anal Chem 2003;75:723–730.
Lautala P, Ulmanen I, Taskinen J. Radiochemical high-performance liquid chromato-
graphic assay for the determination of catechol O-methyltransferase activity towards
various substrates. J Chromatogr B Biomed Sci Appl 1999;736:143–151.
Lee DY. A novel dynamic flow system for sensitive radioactivity detection in LC/MS.
Drug Metab Rev 2006;38 (Suppl 2):33.
Li W, Zhang D, Wang L, Zhang H, Cheng PT, Everett DW, Humphreys WG.
Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies
difference in metabolic pathways leading to unique metabolites. Drug Metab Dispos
2006;34:807–820.
Liberman RG, Tannenbaum SR, Hughey BJ, Shefer RE, Klinkowstein RE, Prakash C,
Harriman SP, Skipper PL. An interface for direct analysis of 14-C in nonvolatile
samples by accelerator mass spectrometry. Anal Chem 2004;76:328–334.
Magyar K, Lengyel J, Klebovich I, Urmos I, Grezal G. Distribution of deramciclane
(EGIS-3886) in rat brain regions. Eur J Drug Metab Pharmacokinet 1998;23:125–
131.
Marathe PH, Shyu WC, Humphreys WG. The use of radiolabeled compounds for
ADME studies in discovery and exploratory development. Curr Pharm Des
2004;10:2991–3008.
Meneses-Lorente G, Sakatis MZ, Schulz-Utermoehl T, DeNardi C, Watt AP. A
quantitative high-throughput trapping assay as a measurement of potential for
bioactivation. Anal Biochem 2006;351:266–272.
Morovjan G, Dalmadi-Kiss B, Klebovich I, Mincsovics E. Metabolite analysis,
isolation, and purity assessment using various liquid chromatographic techniques
combined with radioactivity detection. J Chromatogr Sci 2002;40:603–608.
REFERENCES 315