6.7 Conclusion
The above-described procedures for the synthesis of regioisomerically pure mono-
and diglycerides provide ready access to these materials, and in good yields. By
using stoichiometric quantities of the starting materials, products of high chemical
and isomeric purity are obtained by a novel proprietary process, and without the need
of additional purification steps.
6.7 Conclusion 113
Table 2.Regioisomerically pure 1(3)-sn-monoglycerides.
Product Enzyme Yield (%) Purity (%)
1(3)-sn-monovalerin A 57 93
1(3)-sn-(5^0 -brom)-monovalerin A 52 95
1(3)-sn-(6^0 -brom)-monocaproin A 54 95
1(3)-sn-monoaprylin B 60 91
1(3)-sn-monocaprin C 90 97
1(3)-sn-monodec-9-enoin C 90 96
1(3)-sn-monoundecanoin C 89 96
1(3)-sn-monoundec-10-enoin C 88 96
1(3)-sn-mono-(10^0 -oxo)undecanoin B 60 91
1(3)-sn-monolaurin C 90 98
1(3)-sn-mono-(12^0 -hydroxy)-dodec-9-enoin B 42 95
1(3)-sn-monotridecanoin C 91 97
1(3)-sn-monomyristin C 91 96
1(3)-sn-mono-(13^0 -oxo)-tetradecanoin B 52 92
1(3)-sn-monopentadecanoin C 91 96
1(3)-sn-monopalmitin C 90 95
1(3)-sn-monotearin C 88 96
1(3)-sn-monoolein D 65 99
1(3)-sn-monolinolein F 79 96
1(3)-sn-monoerucain F 71 98
1(3)-sn-mono-(S)-corioloin E 70 95
1(3)-sn-mono-(R)-ricinolin E 66 96
1(3)-sn-mono-(12-(R)-hydroxy)-stearin E 56 98
A¼lipase fromRhizopus delemar
B¼lipase fromMucor miehei(Lipozyme)
C¼lipase fromPseudomonassp.
D¼lipase fromChromobacterium viscosum
E¼lipase fromPenicillium roquefortii
F¼lipase fromRhizopus niveus
Figure 25. Monoglyceride sulfates from monoglycerides.