15.5 References
Began, G., Sudharshan, E., Appu Rao, A.G. (1999), Change in the positional specificity of lipoxygenase 1
due to insertion of fatty acids into phosphatidylcholine deoxycholate mixed micelles,Biochemistry 38 ,
13920–13927.
Belkner, J., Wiesner, R., Ku ̈hn, H., Lankin, V.Z. (1991), The oxygenation of cholesterol esters by the
reticulocyte lipoxygenase,FEBS Lett. 279 , 110–114.
Belkner, J., Wiesner, R., Rathman, J., Barnett, J., Sigal, E., Ku ̈hn, H. (1993), Oxygenation of lipoproteins
by mammalian lipoxygenases,Eur. J. Biochem. 213 , 251–261.
Bild, G.S., Ramadoss, C.S., Axelrod, B. (1977), Dioxygenation by lipoxygenase of lipids containing all-
cis-1,4,7–octatriene moieties,Arch. Biochem. Biophys. 184 , 36–41.
Blee, E. (1998a), Biosynthesis of phytooxylipins: the Peroxygenase pathway,Fett/Lipid 100 , 121–127.
Blee, E. (1998b), Phytooxylipins and plant defense reactions,Prog. Lipid Res. 37 , 33–72.
Borngra ̈ber, S., Browner, M.F., Gillmor, S.A., Gerth, C., Anton, M., Fletterick, R., Ku ̈hn, H. (1999), Shape
and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence de-
terminants for the reaction specificity,J. Biol. Chem., 274 , 37345–37350.
Borngra ̈ber, S., Kuban, R.J., Anton, M., Ku ̈hn, H. (1996), Phenylalanine 353 is a primary determinant for
the positional specificity of mammalian 15-lipoxygenases,J. Mol. Biol. 264 , 1145–1153.
Boyington, J.C., Gaffney, B.J., Amzel, L.M. (1993), Structure of soybean lipoxygenase-I,Biochem. Soc.
Trans. 21 , 744–748.
Brash, A.R. (1999), Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate,J. Biol.
Chem. 274 , 23679–23682.
Brash, A.R., Ingram, C.D., Harris, T.M. (1987), Analysis of a specific oxygenation reaction of soybean
lipoxygenase-1 with fatty acids esterified in phospholipids,Biochemistry 26 , 5465–5471.
Browner, M.F., Gillmor, S.A., Fletterick, R. (1998), Burying a charge,Nature Struct. Biol. 5 , 179.
Bryant, R.W., Schewe, T., Rapoport, S.M., Bailey, J.M. (1985), Leukotriene formation by a purified
reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15–hydroperoxyeicosatetrae-
noic acid to 14, 15-leukotriene A 4 ,J. Biol. Chem. 260 , 3548–3555.
Chen, X.S., Funk, C.D. (1993), Structure–function properties of human platelet 12-lipoxygenase: chi-
meric enzyme and in vitro mutagenesis studies,FASEB J. 7 , 694–701.
Corey, E.J., Nagata, R. (1987), Evidence in favor of an organoiron-mediated pathway for lipoxygenation
of fatty acids by soybean lipoxygenase,J. Am. Chem. Soc. 109 , 8107–8108.
De Groot, J.J.M.C., Garssen, G.J., Vliegenthart, J.F.G., Boldingh, J. (1973), The detection of linoleic acid
radicals in the anaerobic reaction of lipoxygenase,Biochim. Biophys. Acta 326 , 279–284.
De Groot, J.J.M.C., Veldink, G.A., Vliegenthart, J.F.G., Boldingh, J., Wever, R., Van Gelder, B.F. (1975),
Demonstration by EPR spectroscopy of the functional role of iron in soybean lipoxygenases-1,Bio-
chim. Biophys. Acta 377 , 71–79.
Dixon, R.A.F., Jones, R.E., Diehl, R.E., Bennett, C.D., Kargman, S., Rouzer, C.A. (1988), Cloning of the
cDNA for human 5–lipoxygenase,Proc. Natl Acad. Sci. USA 85 , 416–420.
Egmond, M.R., Veldink, G.A., Vliegenthart, J.F.G., Boldingh, J. (1973), C-11H-abstraction from linoleic
acid, the rate-limiting step in lipoxygenase catalysis,Biochem. Biophys. Res. Commun. 54 , 1178–
1184.
Feussner, I., Bachmann, A., Ho ̈hne, M., Kindl, H. (1998), All three acyl moieties of trilinolein are effi-
ciently oxygenated by recombinant His-tagged lipid body lipoxygenase in vitro,FEBS Lett. 431 , 433–
436.
Feussner, I., Wasternack, C. (1998), Lipoxygenase catalyzed oxygenation of lipids,Fett/Lipid 100 , 146–
152.
Feussner, I., Balkenhohl, T.J., Porzel, A., Ku ̈hn, H., Wasternack, C. (1997a), Structural elucidation of
oxygenated storage lipids in cucumber cotyledons–Implication of lipid body lipoxygenase in lipid
mobilization during germination,J. Biol. Chem. 272 , 21635–21641.
Feussner, I., Ku ̈hn, H., Wasternack, C. (1997b), Do specific linoleate 13–lipoxygenases initiateb-oxida-
tion?,FEBS Lett. 406 , 1–5.
Feussner, I., Ku ̈hn, H. (1995), The lipid body lipoxygenase from cucumber seedlings exhibits unusual
reaction specificity,FEBS Lett. 367 , 12–14.
Feussner, I., Wasternack, C., Kindl, H., Ku ̈hn, H. (1995), Lipoxygenase-catalyzed oxygenation of storage
lipids is implicated in lipid mobilization during germination,Proc. Natl. Acad. Sci. USA 92 , 11849–
11853.