Oliver, C. F., Modi, S., Sutcliffe, M. J., Pimrose, W. U., Lian, L. Y., Roberts, G. C. (1997b), A single
mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and
the regiospecificity of hydroxylation,Biochemistry 36 , 1567–1572.
Omura, T., Sato, R. J. (1964), The carbon monoxide-binding pigment of liver microsomes. I. Evidence for
its hemoprotein nature,J. Biol. Chem. 239 , 2370–2378.
Ortiz de Montellano, P. R. Ed. (1995),Cytochrome P450: Structure, Mechanism and Biochemistry,Vol. 2,
New York: Plenum.
Ortiz de Montellano, P. R., Chan, W. K., Tuck, S. F., Kaikaus, R. M., Bass, N. M., Peterson, J. A. (1992),
Mechanism-based probes of the topology and function of fatty acid hydroxylases,FASEB J. 6 , 695–
699.
Oyekan, A. O., McAward, K., McGiff, J. C. (1998), Renal functional effects of endothelins: dependency
on cytochrome P450 – derived arachidonate metabolites,Biol. Res. 31 , 209–215.
Paneghetti, C., Gavagnin, R., Pinna, F., Strukul, G. (1999), New chiral complexes of platinum(II) as
catalysts for the enantioselective Baeyer – Villiger oxidation of ketones with hydrogen peroxide: Dis-
symmetrization of meso-cyclohexanones,Organometallics 18 , 5057–5065.
Park, S. Y., Shimizu, H., Adachi, S., Shiro, Y., Iizuka,T., Nakagawa, A., Tanaka, I., Shoun, H., Hori, H.
(1997), Crystallization, preliminary diffraction and electron paramagnetic resonance studies of a single
crystal of cytochrome P450nor,FEBS Lett. 412 , 346–350.
Peterson, J. A., Graham, S. E. (1998), A close family resemblance: the importance of structure in under-
standing cytochromes P450,Structure 6 , 1079–1085.
Phillips, A. M. F., Romao, C. (1999), Synthesis ofc-butyrolactones by a Baeyer – Villiger oxidation with
hydrogen peroxide, catalysed by methyltrioxorhenium,Chem. Eur. J. 5 , 1767–1770.
Poulos, T. L., Finzel, B. C., Gunsalus, I. C., Wagner, G. C., Kraut, J. (1985), The 2.6–A ̊crystal structure of
Pseudomonas putidacytochrome P-450,J. Biol. Chem. 260 , 16122–16130.
Poulos, T. L., Raag, R. (1992), Cytochrome P450cam: crystallography, oxygen activation, and electron
transfer,FASEB J. 6 , 674–679.
Poulos, T. L., Finzel, B. C., Howard, A. J. (1987), High-resolution crystal structure of cytochrome
P450cam,J. Mol. Biol. 195 , 687–700.
Ravichandran, K. G., Boddupalli, S. S., Hasemann, C. A., Peterson, J. A., Deisenhofer, J. (1993), Crystal
structure of hemoprotein domain of P450 BM-3, a prototype for microsomal P450s,Science 261 , 731–
736.
Rendic, S., Di Carlo, F. J. (1997), Human cytochrome P450 enzymes: a status report summarizing their
reactions, substrates, inducers, and inhibitors,Drug Metab. Rev. 29 , 413–580.
Roman, L. J., Palmer, C. N., Clark, J. E., Muerhoff, A. S., Griffin, K. J., Johnson, E. F., Masters, B. S.
(1993), Expression of rabbit cytochromes P4504Awhich catalyze thex-hydroxylation of arachidonic
acid, fatty acids, and prostaglandins,Arch. Biochem. Biophys. 307 , 57–65.
Ruettinger, R. T., Wen, L.-P., Fulco, A. J. (1989), Coding nucleotide, 5’ regulatory, and deduced amino
acid sequences of P-450 BM-3, a single peptide cytochrome P-450:NADPH-P-450 reductase from
Bacillus megaterium,J. Biol. Chem. 264 , 10987–10995.
Ruettinger, R. T., Fulco, A. J. (1981), Epoxidation of unsaturated fatty acids by a soluble cytochrome P-
450 – dependent system fromBacillus megaterium,J. Biol. Chem. 256 , 5728–5734.
Sallam, L., Naim, N., Zeinel-Abdin Badr, A., El-Refai, A. (1977), Bioconversion of progesterone with cell
preparations withAspergillus niger171,Rev. Latinoam. Microbiol. 19 , 151–153.
Sawamura, A., Kusunose, E., Satouchi, K., Kusunose, M. (1993), Catalytic properties of rabbit kidney
fatty acidx-hydroxylase cytochrome P-450ka2 (CYP4A7),Biochim. Biophys. Acta 1168 , 30–36.
Scheller, U., Zimmer, T., Becher, D., Schauer, F., Schunck, W. H. (1998), Oxygenation cascade in con-
version ofn-alkanes toa,x-dioic acids catalyzed by cytochrome P450 52A3,J. Biol. Chem. 273 ,
32528–32534.
Scheller, U., Zimmer, T., Kargel, E., Schunck, W. H. (1996), Characterization of the n-alkane and fatty
acid hydroxylating cytochrome P450 forms 52A3 and 52A4,Arch. Biochem. Biophys. 328 , 245–254.
Schlichting, I., Berendzen, J., Chu, K., Stock, A. M., Maves, S. A., Benson, D. E., Sweet, R. M., Ringe, D.,
Petsko, G. A., Sligar, S. G. (2000), The catalytic pathway of cytochrome P450cam at atomic resolution,
Science 287 , 1615–1622.
Schneider, S., Wubbolts, M.G., Sanglard, D., Witholt, B. (1998), Biocatalyst engineering by assembly of
fatty acid transport and oxidation activities for in vivo application of cytochrome P-450BM-3 mono-
oxygenase,Appl. Environ. Microbiol. 64 , 3784–3790.
tina sui
(Tina Sui)
#1