Front Matter

2.2 Fractionation of fatty acids and other lipids by lipase-catalyzed reactions 33

Table 3.Enrichment of n-3 unsaturated fatty acids and their derivatives via kinetic resolution catalyzed
by lipases.

Lipase from Reaction Fatty acid enriched Reference

R. miehei Selective esterification
of fatty acids of marine
oil with methanol

n-3 Docosahexaenoic

acid in unesterified

fatty acids

Langholz et al., 1989

Rapeseed,R. mieheiSelective esterification
of fatty acids of fish oil
withn-butanol

n-3 Docosahexaenoic

acid in unesterified

fatty acids

Hills et al., 1990b;

Jachmania ́n and Mukher-

jee, 1996

C. rugosa Selective hydrolysis
of fish oil triacylglycerols

n-3 Docosahexaenoyl

moieties in tri-, di- and

monoacylglycerols

Hoshino et al., 1990;

Tanaka et al., 1992; 1993;

Moore and McNeill, 1996;

McNeill et al., 1996; Wa-

nasundara and Shahidi,

1998; Rice et al., 1999

Rhizopus niveus Selective hydrolysis
of fish oil triacylglycerols

n-3 Docosahexaenoyl

moieties in monoacyl-

glycerols

Yadwad et al., 1991

R. miehei Interesterification of
cod liver oil with a
fatty acid mixture or
its ethyl esters enriched
in n-3 20 : 5 and
n-3 22 : 6

n-3 Eicosapentaenoyl

and n-3 docosahexaenoyl

moieties in triacylglycerols

Haraldsson and

Almarsson, 1991

R. miehei Interesterification of
cod liver oil with a
fatty acid mixture
enriched in n-3 20 : 5
and n-3 22 : 6

n-3 Docosahexaenoyl

moieties in acylglycerols

Yamane et al., 1992; 1993

R. miehei Interesterification
of vegetable oils
with n-3 20 : 5 and
n-3 22 : 6 fatty acids
or their methyl or
ethyl
esters

n-3 Eicosapentaenoyl

and n-3 docosahexa-

enoyl moieties in

triacylglycerols

Sridhar and Lakshminar-

ayana, 1992; Zu-yi and

Ward, 1993; Huang and

Akoh, 1994; Huang et al.,

1994

Pseudomonassp. Interesterification of
sardine oil with a fatty
acid mixture enriched
in n-3 20 : 5 and n-3
22 : 6

n-3 Eicosapentaenoyl

and n-3 docosahexaenoyl

moieties in acylglycerols

Adachi et al., 1993

Pseudomonassp. Interesterification
of fish oil with alcohols

n-3 Eicosapentaenoyl

and n-3 docosahexaenoyl

moieties in monoacyl-

glycerols

Zu-yi and Ward, 1993a;

1993b

C. antarctica Esterification of glycerol
or alkylglycerols with
n-3 20 : 5 and n-3 22 : 6
fatty acids

n-3 Eicosapentaenoyl and

n-3 docosahexaenoyl

moieties in triacylglycer-

ols and alkylacylglycerols,

respectively

Haraldsson et al., 1993;

Haraldsson and Thoraren-

sen, 1994