Cell Language 181“6x9” b2861 The Cell Language Theory: Connecting Mind and MatterThe order of words in a sentence can be changed with relative ease
by the speaker or writer, within grammatical constraints, but the order
of letters in a word is more or less fixed by convention and cannot be
changed by individuals. In other words, the first articulation has a
greater degree of freedom (for change) than the second articulation, and
this dual property of the human language is reminiscent of the dual
properties of organic molecules called “conformation” and “configura-
tion” (see Table 3.6).
In 2012 [25], the concept of double articulation was extended to
include the third articulation as defined in Table 4.3 reproduced
from [25].4.2.2 Rule-Governed Creativity
Another important principle to be imported into biology from linguistics is
the so-called “rule-governed creativity”, referring to the fact that the
human brain is endowed with the capacity to generate (and understand) an
indefinitely large number of meaningful sentences constructed on the basisTable 4.3 Triple articulations in cell and human languages.
Parameters Human Language Cell Language- Key material
component
Book DNA- Size of signs Macroscopic (e.g., words) Microscopic (e.g., molecules)
- Reader/effector The human brain The cell
- First
articulation
Words → Sentences Non-covalent structures (e.g., 1-D
amino acid sequence → 3-D protein
conformations)- Second
articulation
Letters → Words Covalent structures (e.g., amino acids →
1-D protein primary structures)- Third
articulation
Sentences → Texts Gradient structures (e.g., diffusible
molecules & ions → transmembrane
ion gradients, intracellular mechanical
stress gradients [193], intracellular
ion, and metabolite gradients.
(Gradients and dissipative structures
are synonymous; my addition)b2861_Ch-04.indd 181 17-10-2017 11:58:54 AM