208 The Cell Language Theory: Connecting Mind and Matterb2861 The Cell Language Theory: Connecting Mind and Matter “6x9”Table 4.14 The logical and physical requirements for the mechanism of the origin of
molecular messages (as specified by H. Pattee) are met by the combination of the
Anderson model of the origin of biological information and the Princetonator.
Pattee’s Constraints
on Mechanisms of the
Origin of Life [89]Satisfied byAnderson’s Model The Princetonator- Primeval
ecosystem
The “RNA soup”
on the surface
of the earth
subjected to
thermal cycling- Simple rules Conformon production and utilization (see
Figure 3.30) - Switches Frustrated regions of RNA harboring
conformons (see Figure 4.10) - Open-ended
evolvability
Thermally accessible conformations
(called virtual conformons [7, p. 136])
of RNA fragments that can drive self-
replication when reified to real
conformons upon coupling to
exergonic chemical reactions, obeying
the GFCP [7, pp. 50–56]. Due to
thermal motions implicated, there is a
finite probability of errors occurring
during the conformon-driven
copolymerization process, thus
leading to mutations and open-ended
evolution [92]- Stability It is possible that n catalytically active
molecular species (CAMS) must be
co-localized in a small spatial volume
(to be called the catalytic site) to
effectuate spontaneous copolymeriz-
ations (see the Franck–Condon
state defined on p. 433 in [12] and
Figure 3.30). If the probability of such
a co-localization is P and the average
probability of individual CAMS being
located in the catalytic site is p, the
following relation holds: P = pn.
(Continued)
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