Cell Language 219“6x9” b2861 The Cell Language Theory: Connecting Mind and MatterFigure 4.14 Music visualized using a CymaScope. (a) Female vocal sounds. (b) 12 piano
notes. (c) Water wave images (or aquawaves) of the sounds generated by alive yeast cell,
the period of oscillations of the sound being about 2 s. Each image is taken about 1–2 s
apart. Screen shots made from the video at https://www.youtube.com/watch?v=P3cTxdGj2zI.
(d) Human brainwave frequencies visualized. a rhythm = 8–13 Hz (relaxed waking state);
b rhythm = 18–22 Hz (rational waking state); θ rhythm = 4–7 Hz (meditative state); d
rhythm = 1–3 Hz (deep sleep state). All these images were retrieved from https://www.
cymascope.com/shop/cymaart-prints/ or http://www.cymascope.com/cyma_research/
musicology.html on 10/11/2016.4.14 Sonocytology or “Cytocymatics”
James Gimzewski of UCLA coined the term “sonocytology” [523] when he
discovered that a single yeast cell could generate sound (i.e., periodic
motions or waves) as detected by the atomic force microscopy (AFM). The
sound records thus obtained were visualized by J. S. Reid using his
CymaScope, as shown in row C in Figure 4.14. Cell sounds are the second-
ary, transformed signals of the primary signal which is cell vibrations that
are measured by AFM. So one alternative name of the field that studies cell
vibrations may be “cytocymatics” (cyto- = cell; -cymatics = the study of
waves). Thus defined we can include in cytocymatics not only the study of
cell sounds (as sonocytology implies), but also the study of chemical con-
centration waves, such as intracellular Ca2+ waves (see [25, Figure 3.2]),
RNA concentration waves (see [25, Figure 15.1]), etc. Cell vibrations are
most likely the result of periodic influxes and outflows of water molecules
through the cell membrane (either aquaporin-mediated or aquaporin-
independent depending on cell types) leading to cell volume changes. The
sounds of a beating yeast cell are very similar to the sounds of the beating
human heart, as evident in the video available at https://www.youtube.com/
watch?v=P3cTxdGj2zI. It may be that, just as the human heart undergoes
the contraction–relaxation cycle exhibiting regular heart beats with 1–3 Hz,
so individual heart cells may also undergo the contraction–relaxation cycle
mediated by the cytoskeleton producing cell sounds with about 0.5 Hz,
pumping water in and out of heart cells. Consistent with this postulate, vari-
ous isoforms of aquaporins have been found in the heart tissues [526, 527].
The only additional postulate that is needed to account for the approximate
equality of the periodicities between the motions of the myocytes and theb2861_Ch-04.indd 219 17-10-2017 11:59:06 AM