Cell Language Theory, The: Connecting Mind And Matter

306 The Cell Language Theory: Connecting Mind and Matter

b2861 The Cell Language Theory: Connecting Mind and Matter “6x9”

tissue (N), tumor before (BE) drug treatment (doxorubicin, 16 weeks),

and tumor after (AF) drug treatment in vivo (Figure 7.10). The fourth

sample from tumor after (AF’) drug treatment in vitro was not obtained by

Perou et al. but would be needed if the ribonoscopic method described

here is to be utilized for personalized medicine.

7.3.1 The Mechanism Circle-Based Analysis

The human breast cancer data measured by Perou et al. [306] can be

organized as shown in Table 7.2. The original mRNA data of Perou et al.

[306] in the three columns denoted as N (normal), BE (tumor before treat-

ing with the anticancer drug, doxorubicin), and AF (tumor after treating

with drug) in Table 7.2 are processed through steps (1)–(3) and the results

are presented in Figure 7.12.

Figure 7.10 The four types of tissues that are required to generate the molecular data,

e.g., RNA sequences and differential expression patterns measured with microarrays or

equivalent techniques. N, BE, and AF are needed for generating the molecular data (see

Table 7.2) for theragnostics (i.e., therapeutic and diagnostic purposes), while N, BE, AF,

and AF’ will be needed to generate the molecular data for personalized therapy and per-

sonalized medicine or precision medicine. For the sake of simplicity, the symbol AF is

used to indicate either AF or AF’, whenever no confusion can arise under the context of

the discussion involved.

Tumor Tissue After

Drug Treatment in vitro

(AF’)

Patient X

Biopsy

Normal Tissue Tumor Tissue Before Tumor Tissue After

Drug Treatment Drug Treatment in vivo

(N) (BE) (AF)

Tissue culture

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