Cell Language Theory, The: Connecting Mind And Matter

The Universality of the Planckian Distribution Equation 339

“6x9” b2861 The Cell Language Theory: Connecting Mind and Matter

transition state (denoted as C‡) by thermal fluctuations (also called

Brownian motions), leading to catalysis [25, Section 11.3.3]. One of the

differences between Figures 8.4 (a) and (b) is that atoms exist in a com-

mon ground electronic state from which they access different transition

states, whereas an en enzyme molecule is thought to exist in multiple

ground states, all reaching a common transition state for catalysis.

8.2.3 RASER Model of Enzyme Catalysis

RASER is an acronym derived from rate amplification based on the

substrate-enhanced reaction rates, in analogy to laser, or light amplifica-

tion based on stimulated emission of radiation. There is the possibility

that, just as the BRE of Planck was found to apply to the single-mole-

cule enzyme turnover times of cholesterol oxidase [25, Chapter 11], so

the subatomic mechanisms underlying the phenomenon of laser may

Figure 8.4 The postulated isomorphism between energy quantization in atoms and the

discretization of the conformational states (and hence of Gibbs free energy levels) in

enzymes. (a) The quantization of the energy levels of the electrons in an atom suggested by

the fitting of the blackbody radiation spectra with the PRE discovered in 1900 [87]. (b) In

analogy to the quantization of the energy levels of electron in an atom entailed by the

Planck’s radiation law, i.e., Eq. (8.1), it is postulated that the fitting of the single-molecule

turnover time histogram of cholesterol oxidase by a generalized PRE (also called PDE), Eqs.

(8.2) or (8.3), implied a similar quantization of energy levels of enzymes most likely due to

their existence in discrete conformational states, denoted as Ci, where the index i running

from 1 to n, the number of conformational states of an enzyme [25, Chapters 11 and 12].

E 6

E 5

E 4

E 3

E 2

E 1

E 0

C‡

C 5

C 4

C 3

C 2

C 1

C 0

Blackbody Radiation Enzyme Catalysis

(a) (b)

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