The Universality of the Planckian Distribution Equation 367“6x9” b2861 The Cell Language Theory: Connecting Mind and MatterUnderlying Statement (8.15) is the assumption that increasing random-
ness (or entropy) necessarily decreases information (i.e., order), which seems
to violate the FLI, Statement (8.12a).In contrast to Statement (8.15), the infusion of psilocybin actually
increased order as measured by IP, from 1.03 to 1.37 bits, indicating
that the psilocybin infusion increases both entropy and information.
(8.16)Statement 8.16 is mathematically possible because psilocybin infu-
sion could have increased both the denominator, AUC(GLE), and the
numerator, AUC(PDE), in Eq. (8.10) but the latter more than the former,
resulting in an increase in IP. If this interpretation of the psilocybin effects
on brain neurohemodynamics proves to be correct, it would be possible to
conclude thatPsilocybin increases order in the human brain, rather than decreases it
as predicted by the entropic brain hypothesis. (8.17)For the purpose of facilitating discussions, Statements (8.16) and
(8.17) may be referred to as the “informational brain hypothesis (IBH)” to
contrast with EBH, Statement (8.15). The differences and similarities
between EBH and IBH are summarized in Table 8.4.Table 8.4 A comparison between the entropic [341] and informational brain [547, 563]
hypotheses.
EBH IBH
Psilocybin
inducesIncrease in entropy Increase in entropy as measured by
AUC(GLE)
(Not available) Increase in selection as measured by
AUC(PDE)/AUC(GLE)
(Not available) Increase IP as measured by Log 2 [AUC(PDE)/
AUC(GLE)]
Increase in DMN activities Increase in DMN activities
PDE = Planckian distribution equation, (8.2) or (8.3) [27, 442]. GLE = Gaussian-like equation, (8.9)
[27, 442]. AUC = area under the curve. IP = Planckian information, (8.10). DMN = default mode
network [341].b2861_Ch-08.indd 367 17-10-2017 12:09:19 PM