Cell Language Theory, The: Connecting Mind And Matter

426 The Cell Language Theory: Connecting Mind and Matter

b2861 The Cell Language Theory: Connecting Mind and Matter “6x9”

f g

Neuroanatomy Neural networkNeural Activity

(Long-term memory) (Working memory) (Behavior)

h

Figure 10.18 Practopoiesis [388] as semiosis. f = memory recall; g = anapoiesis; h =

genetic constraint, genetic information flow. The names of the nodes/vertices and the

arrows/edges and their meanings are from [388]. Anapoiesis refers to the process of recon-

structing the specific knowledge demanded by a given moment in time by retrieving

needed knowledge from a general knowledge stored in multi-level cognitive systems [566].

f g

( A+ B) (X+ Y) (D+ E)

h

Figure 10.19 Self-Organizing Chemical Reaction (SOCR) as a semiosis. The Brusselator,

a prototypical SOCR, is a commutative triangle embodying ITR and performs semiosis at

the molecular level. A, B = reactants; X, Y = transient intermediates; C, D = products;

f = production step, g = destruction step, h = information flow (i.e., the molecular struc-

tures of E and E’ are determined by those of A and B mediated by X and Y).

f g

Amino Acid SequenceConformsCatalysis

h

Figure 10.20 Enzyme catalysis as semiosis. f = protein folding; g = generalized Franck-

Condon principle (GFCP) [12] and pre-fit process (see Section 3.2.9); h = information flow

(supported by the free energy dissipation accompanying Steps f and g). Conformons are

defined as the mechanically strained conformations of proteins that possess both mechanical

energy and genetic information to drive enzymic catalysis (Section 3.4). As such, they rep-

resent a subset of all the possible conformational strains that can be generated by a sequence

of amino acids that has been selected by the biological evolution for their catalytic role in

living processes. In other words, not all conformational strains generated within a protein

can contribute to catalysis but only those that have the right properties for catalysis.

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