60 The Cell Language Theory: Connecting Mind and Matterb2861 The Cell Language Theory: Connecting Mind and Matter “6x9”Figure 3.4 The supermolecule defined as the unit of the structure and function of the
mitochondrial inner membrane carrying out all coupled processes in mitochondria, includ-
ing oxidative phosphorylation (oxphos), active transport, and energized transhydrogenation.
(a) The main structural components of the supermolecule are: (i) ETC (of which there are
four complexes, namely I, II, III, and IV), (ii) ATP synthase, and (iii) the stalk connecting
ETC to ATP synthase. The base piece of the stalk sector symbolized as a cube supporting
the stalk is later identified with the F 0 component of the F 0 F 1 –ATPase (see the upper right-
hand corner of Figure 3.35). (b) The side view of the complete electron transport chain
coupled to the three ATP synthases that together catalyzes the oxidation of one NADH
molecule with an oxygen atom to produce one water molecule while producing(a)(b)ATPaseStalk sector
electron transfer
proteinsProton transfer
proteinsC 1C 1
b
b b bH+H+H+H+e–e–
e–e–nhFe nhfeQH 2Coupling site IATPase2e–
2H+ 2H+2e–
2H+
H 2 O2e–ATPase ATPaseCoupling site II Coupling site III2C+3DPNH 2 + Q 2C+3^1 / 2 O 2b2861_Ch-03.indd 60 17-10-2017 11:46:10 AM