Hansson, O., Petersen, A., Leist, M., Nicotera, P., Castilho, R.F. and Brundin, P. (1999)
Transgenic mice expressing a Huntington’s disease mutation are resistant to quinolinic
acid-induced striatal excitotoxicity. Proc. Natl Acad. Sci. U.S. A. 96:8727–8732.
Harada, H., Andersen, J.S., Mann, M., Terada, N. and Korsmeyer, S.J. (2001) p70S6 kinase
signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. Proc.
Natl Acad. Sci. U.S.A. 98:9666–9670.
Harada, H., Becknell, B., Wilm, M., Mann, M., Huang, L.J., Taylor, S.S., Scott, J.D. and
Korsmeyer, S.J. (1999) Phosphorylation and inactivation of BAD by mitochondria-
anchored protein kinase A. Mol.Cell 3:413–422.
Harding, H.P., Novoa, I., Zhang, Y., Zeng, H., Wek, R., Schapira, M. and Ron, D. (2000a)
Regulated translation initiation controls stress-induced gene expression in mammalian
cells. Mol. Cell 6:1099–1108.
Harding, H.P., Zhang, Y., Bertolotti, A., Zeng, H. and Ron, D. (2000b) Perk is essential for
translational regulation and cell survival during the unfolded protein response. Mol. Cell
5:897–904.
Harding, H.P., Zhang, Y. and Ron, D. (1999) Protein translation and folding are coupled
by an endoplasmic-reticulum-resident kinase. Nature 397: 271–274.
Hardy, J. (1997) Amyloid, the presenilins and Alzheimer’s disease. Trends Neurosci. 20:154–
159.
Harris, M.H., Vander Heiden, M.G., Kron, S.J. and Thompson, C.B. (2000) Role of
oxidative phosphorylation in Bax toxicity. Mol. Cell. Biol. 20:3590–3596.
Hartman, P.S. and Herman, R.K. (1982) Radiation-sensitive mutants of Caenorhabditis
elegans. Genetics 102:159–178.
Harvey, K.J., Lukovic, D. and Ucker, D.S. (2000) Caspase-dependent Cdk activity is a
requisite effector of apoptotic death events. J.Cell Biol. 148:59–72.
Harvey, N., Trapani, J.A., Fernandes-Alnemri, T., Litwack, G., Alnemri, E.S. and Kumar,
S. (1996) Processing of the Nedd2 precursor by ICElike proteases and granzyme B. Genes
Cells 1:673–685.
Harvey, N.L., Butt, A. and Kumar, S. (1997) Functional activation of Nedd2/ICH-1
(caspase-2) is an early process in apoptosis. J.Biol. Chem. 272:13134–13139.
Harvey, N.L., Daish, T., Mills, K., Dorstyn, L., Quinn, L.M., Read, S.H., Richardson, H.
and Kumar, S. (2001) Characterization of the Drosophila caspase, DAMM. J.Biol. Chem.
276:25342–25350.
Hasegawa, H., Kiyokawa, E., Tanaka, S., Nagashima, K., Gotoh, N., Shibuya, M., Kurata,
T. and Matsuda, M. (1996) DOCK180, a major CRK-binding protein, alters cell
morphology upon translocation to the cell membrane. Mol.Cell.Biol. 16:1770–1776.
Hashimoto, Y., Niikura, T., Tajima, H., et al. (2001) A rescue factor abolishing neuronal cell
death by a wide spectrum of familial Alzheimer’s disease genes and Abeta. Proc. Natl Acad.
Sci. U.S.A. 98:6336–6341.
Hassane, D.C., Lee, R.B., Mendenhall, M.D. and Pickett, C.L. (2001) Cytolethal distending
toxin demonstrates genotoxic activity in a yeast model. Infect. Immun. 69:5752–5759.
Hawkins, C., Wang, S. and Hay, B. (1999) A cloning method to identify caspases and their
regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila
caspase DCP-1. Proc. Natl Acad. Sci. U.S.A. 96:2885–2890.
Hawkins, C.J., Yoo, S.J., Peterson, E.P., Wang, S.L., Vernooy, S.Y. and Hay, B.A. (2000)
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated
by DIAP1, HID, and GRIM. J.Biol.Chem. 275: 27084–27093.
REFERENCES 255