Genetics of Apoptosis

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inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly. EMBO J. 19:
5418–5428.
Honegger, T., Zürrer, D. and Tardent, P. (1989) Oogenesis in Hydra carnea: a new model
based on light and electron microscopic analyses of oocyte and nurse cell differentiation.
Tissue Cell 21:381–393.
Hong, S.Y., Yoon, W.H., Park, J.H., Kang, S.G., Ahn, J.H. and Lee, T.H. (2000)
Involvement of two NF-kappa B binding elements in tumor necrosis factor alpha-,
CD40-, and Epstein-Barr virus latent membrane protein 1-mediated induction of the
cellular inhibitor of apoptosis protein 2 gene. J.Biol. Chem. 275:18022–18028.
Horng, T. and Medzhitov, R. (2001) Drosophila MyD88 is an adapter in the Toll signaling
pathway. Proc. Natl Acad. Sci. U.S.A. 98:12654–12658.
Hsu, H., Shu, H.B., Pan, M.G. and Goeddel, D.V. (1996) TRADD-TRAF2 and TRADD-
FADD interactions define two distinct TNF receptor 1 signal transduction pathways.
Cell 84:299–308.
H s u , H. , Xi o n g, J. an d G oe d de l , D. V. (1995) The TNF receptor 1-associated protein TRADD
signals cell death and NF-kappa B activation. Cell 81:495–504.
Hsu, S.Y., Kaipia, A., McGee, E., Lomeli, M. and Hsueh, A.J. (1997) Bok is a proapoptotic
Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with
selective anti-apoptotic Bcl-2 family members. Proc. Natl Acad. Sci. U.S.A. 94:12401–
12406.
Hsu, Y.T., Wolter, K.G. and Youle, R.J. (1997) Cytosol-to-membrane redistribution of Bax
and Bcl-X(L) during apoptosis. Proc. Natl Acad. Sci. U.S.A. 94: 3668–3672.
Hsu, Y.T. and Youle, R.J. (1998) Bax in murine thymus is a soluble monomeric protein that
displays differential detergent-induced conformations. J.Biol. Chem. 273:10777–10783.
Hu, S., Vincenz, C., Buller, M. and Dixit, V.M. (1997) A novel family of viral death effector
domain-containing molecules that inhibit both CD-95—and tumor necrosis factor
receptor-1-induced apoptosis. J.Biol. Chem. 272:9621– 9624.
Hu, S. and Yang, X. (2000) dFADD, a novel death domain-containing adapter protein for
the Drosophila caspase DREDD. J.Biol.Chem. 275:30761–30764.
Huang, B., Eberstadt, M., Olejniczak, E.T., Meadows, R.P. and Fesik, S.W. (1996) NMR
structure and mutagenesis of the Fas (APO-1/CD95) death domain. Nature 384:638–
641.
Huang, D.C., O’Reilly, L.A., Strasser, A., Cory, S., Chou, J.J., Li, H., Salvesen, G.S., Yuan,
J. and Wagner, G. (1997) The anti-apoptosis function of Bcl-2 can be genetically
separated from its inhibitory effect on cell cycle entry. EMBO J. 16: 4628–4638.
Huang, D.C.S. and Strasser, A. (2000) BH3-only proteins—essential initiators of apoptotic
cell death. Cell 103:839–842.
Huang, Y., Park, Y.C., Rich, R.L., Segal, D., Myszka, D.G. and Wu, H. (2001) Structural
basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.
Cell 104:781–790.
Huang, Z. (2000) Bcl-2 family proteins as targets for anticancer drug design. Oncogene 19:
6627–6631.
Hunter, J.J. and Parslow, T.G. (1996) A peptide sequence from Bax that converts Bcl-2 into
an activator of apoptosis. J.Biol. Chem. 271:8521–8524.
Hymowitz, S.G., Christinger, H.W., Fuh, G., Ultsch, M., O’Connell, M., Kelley, R.F.,
Ashkenazi, A. and de Vos, A.M. (1999) Triggering cell death: the crystal structure of
Apo2L/TRAIL in a complex with death receptor 5. Mol. Cell 4:563–571.


258 GENETICS OF APOPTOSIS

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