Yamamoto, K., Ichijo, H., Korsmeyer, S.J., Chou, J.J., Li, H., Salvesen, G.S., Yuan, J. and
Wagner, G. (1999) BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal
protein kinase pathway normally activated at G(2)/M. Mol. Cell. Biol. 19:8469–8478.
Yamashima, T. (2000) Implication of cysteine proteases calpain, cathepsin and caspase in
ischemic neuronal death of primates. Prog. Neurobiol. 62:273–295.
Yan, M., Marsters, SA., Grewal, I.S., Wang, H., Ashkenazi, A. and Dixit, V.M. (2000)
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity.
Nat. Immunol. 1:37–41.
Yang, E., Zha, J., Jockel, J., Boise, L.H., Thompson, C.B. and Korsmeyer, S.J. (1995) Bad,
a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell
80:285–291.
Yang, X., Chang, H.Y. and Baltimore, D. (1998a) Autoproteolytic activation of pro-caspases
by oligomerization. Mol. Cell 1:319–325.
Yang, X., Chang, H.Y. and Baltimore, D. (1998b) Essential role of CED-4 oligomerization
in CED-3 activation and apoptosis. Science 281:1355–1357.
Yang, X., Khosravi-Far, R., Chang, H.Y. and Baltimore, D. (1997) Daxx, a novel Fas-binding
protein that activates JNK and apoptosis. Cell 89:1067–1076.
Yaoita, H., Ogawa, K., Maehara, K. and Maruyama, Y. (2000) Apoptosis in relevant clinical
situations: contribution of apoptosis in myocardial infarction. Cardiovasc. Res. 45:630–
641.
Ye, J., Rawson, R.B., Komuro, R., Chen, X., Dave, U.P., Prywes, R., Brown, M.S. and
Goldstein, J.L. (2000) ER stress induces cleavage of membrane-bound ATF6 by the same
proteases that process SREBPs. Mol. Cell 6:1355–1364.
Ye, Y., Meyer, H.H. and Rapoport, T.A. (2001) The AAA ATPase Cdc48/p97 and its partners
transport proteins from the ER into the cytosol. Nature 414: 652–656.
Yeh, W.C., Hakem, R., Woo, M. and Mak, T.W. (1999) Gene targeting in the analysis of
mammalian apoptosis and TNF receptor superfamily signaling. Immunol. Rev. 169:283–
302.
Yeh, W.C., Itie, A., Elia, A.J., et al. (2000) Requirement for Casper (c-FLIP) in regulation of
death receptor-induced apoptosis and embryonic development. Immunity 12:633–642.
Yeh, W.C., Pompa, J.L., McCurrach, M.E., et al. (1998) FADD: essential for embryo
development and signaling from some, but not all, inducers of apoptosis. Science 279:
1954–1958.
Yeh, W.C., Shahinian, A., Speiser, D., et al. (1997) Early lethality, functional NF-kappaB
activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice.
Immunity 7:715–725.
Yin, X.M., Oltvai, Z.N. and Korsmeyer, S.J. (1994) BH1 and BH2 domains of Bcl-2 are
required for inhibition of apoptosis and heterodimerization with Bax. Nature 369:321–
323.
Yin, X.M., Wang, K., Gross, A., Zhao, Y., Zinkel, S., Klocke, B., Roth, K.A. and Korsmeyer,
S.J. (1999) Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.
Nature 400:886–891.
Yoneda, T., Imaizumi, K., Oono, K., Yui, D., Gomi, F., Katayama, T. and Tohyama, M.
(2001) Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through
tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to
the ER stress. J.Biol. Chem. 276: 13935–13940.
Yoshida, H., Haze, K., Yanagi, H., Yura, T. and Mori, K. (1998a) Identification of the cis-
acting endoplasmic reticulum stress response element responsible for transcriptional
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