Genetics of Apoptosis

(Barry) #1

Index


Note: Page references in bold refer to Tables; those in italics refer to Figures
ABCB1 206
activation-induced cell apoptosis (ACID) 21–
1
adapter domains 77–87
adenine nucleotide translocator (ANT) 58,
108, 121
ANT-1 207, 208, 209
ANT-2 207
aging in yeasts 147
AIDS, augmentation of death receptor-
induced apoptosis in 24
Akt 15
ALG-2 205
ALG-3 205
ALG-4 205
all-trans-retinoic acid (ATRA) 27–7
Alzheimer’s disease 115–11, 202, 205, 206
anoikis (Bmf) 65
Apaf-1 6, 83, 94, 95, 204
Apaf-1/caspase-9 apoptosome 38, 40, 96
Apo2L see TRAIL
Apo3 1, 6
Apo3L (TWEAK) 1
apoptin 209
apoptosis-inducing factor (AIF) 156–1, 225
apoptosis-like programmed cell death 213
apoptosis signal regulating kinase (ASK1) 8,
221
apoptosome complex 6, 38, 40, 96
Arabidopsis
bax expression in 141
cDNA library 148
Arabidopsis thaliana ethylene-responsive
element-binding protein (AtEBP) 148


AP-ARPase domain (NB-ARC domain) 93–9
ARTS 205
ASC/Pycard 84, 94
ASF1/CIA1 144
ATF6 99, 117
autoimmune lymphoproliferative syndrome
(ALPS, Calane Smith syndrome) 24
avian CAR1 1

baculovirus IAP repeat (BIR) 12
Bad 42, 44, 126, 130
BAFFR 77
Bak 52, 103–104, 126, 127, 129, 131
competition with Bcl-2 family 12
mitochondrial disruption by 6–8
Bap31 64, 112–10
Bax gene 26
Bax 48–8, 51, 53, 56, 61–63, 17–18, 103–
104, 126, 127–3, 131
channels in mitochondria 131–8, 136
competition with Bcl-2 family 12
COOH-terminal hydrophobic sequence
65–3
mitochondrial distruation by 6–8
and mitochondrial respiration 138–2
Bax-ANT channels in mitochondria 137
Bax-VDAC channels in mitochondria 134–
30
Bcl-2 29, 48, 61–63, 68
mutational studies 59
Bcl-2 family xviii, 44, 48–69, 90–8, 90, 125
BH3 domains 52
Bcl-2—family—continued
chronology 49

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